DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cd and skpo-3

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	NP_495511.1	Gene:	skpo-3 / 174191	WormBaseID:	WBGene00017968	Length:	1000	Species:	Caenorhabditis elegans

Alignment Length:	767	Identity:	221/767 - (28%)
Similarity:	339/767 - (44%)	Gaps:	144/767 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 PSFFFVVNGSDSELAP------------NRPL------------PDEPAAEWALQQAALGHHDGA 120
            |:|.||     .::||            .|||            |.........|..|..|.
Worm   321 PTFAFV-----PDIAPVTRFFVQRQPVTRRPLPAVFFTTRRTFPPPTTTTTTTTQAPATTHF--- 377

  Fly   121 QAVSAGIKALGDREILEEGLQPNEVNTPSFRHYRSLSTNP--EARKLARRGYV------ENQATI 177
                       .||........:.:||.|....|.:..:|  .|..:.|...|      ..:.|:
Worm   378 -----------TREFTPPPTTRSFINTGSNARCRDIINDPIVAAEDMWRERLVVATEDNTRRQTV 431

  Fly   178 DIAKRFNYTKQPGRSNIGWGPKIVLPDPTVLRLECD----FNARYRRSTGVCNNKQHPRTYGASM 238
            |:       .|..|||..     ....|.:...:|:    :||.:|...|.|||.:.....|||.
Worm   432 DL-------DQVIRSNTA-----NACTPRLDEADCEANICYNAMFRTLDGTCNNMKGEPLRGASY 484

  Fly   239 VPYRRMVSPDYADGIAAPRVSHHGRL-----PPARQVSLKIHRSSYETDS-NFTVMLAVFGQFMD 297
            .||.|::...|.:.::.|    .|.|     |..|:::.::..|....:| ::..::..||||:.
Worm   485 RPYTRLLPTIYDNEVSEP----VGSLFTDARPSPREITRRLTSSQASVESPDYNALIMQFGQFIS 545

  Fly   298 HDITATSLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYYKQYNISCMNFVRSAP-APTGRF 361
            ||:..|:|..|.:   .:.|...|    ..|..|.|..||.........|:...||:| ..:|..
Worm   546 HDMAKTTLVPSSK---CNVCQNIT----SRCMSVPITFDDSNANFRQAQCIRVSRSSPICGSGNL 603

  Fly   362 GPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSLR--MFVTDDGRQLLPISSNPADGC-NRV 423
            .||.|||:.|.:||||.:||:......:.|...:|.|:  ||   :|:..||...|.   | ||.
Worm   604 KPRQQLNENTGYIDASPIYGSSVHDSKKFRDGNSGFLKLPMF---NGKAFLPFDQNK---CRNRG 662

  Fly   424 QMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEARKILGAQM 488
            |.:.:    |.:||.|.|..:.|::.|.::...||.|....:..||||:.|||||||||::|||:
Worm   663 QCSVI----FTAGDSRVNLFVGLSAWHTIFTEEHNRLVTAFKRLNPHWDGERLYQEARKMIGAQV 723

  Fly   489 AHITYNEFLPVLLGKN----ISEAKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAFRFAHTLLP 549
            ..|.|.|:||.:||.:    :.:.:|             ||.:||.::||.|.:|||||.|.::.
Worm   724 QAIVYREWLPKVLGASFATVVGDYRG-------------YDSDVDSTVANEFTSAAFRFGHGMIQ 775

  Fly   550 GLFNISRDNSTPE----AIELHKMLFNPFSLWAEHGIDHALMTAANTPVMQVDRFFSLEVTQKLF 610
            ..:. ..|||...    |:...|...:...|..|.|:|..:....:..|.:..| .:..||:.:|
Worm   776 EFYQ-RLDNSFRNISFGALPFQKGTLHSDVLVNEGGVDPLIRGMFSQNVKRPQR-VTTTVTENMF 838

  Fly   611 EGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLPTVDTWEEMSQAIDN-ATLDSIRQI 674
            ..|          ||.::|||||||||.|:|..:|..|.:.|...:|.:|:.|.| .|.:.:::|
Worm   839 GST----------DLSTINIQRGRDHGHPAYVKYRELCGMGTAFNFEHLSREILNTGTRNKLQEI 893

  Fly   675 YESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIY 739
            |.|...:|::.|||.|.|:...:.||.::|::..||.|.:.||..:||   .|..|::.||.||.
Worm   894 YGSVDKIDLWVGALLEDPIIRGLVGPTVACIIGPQFKRTRDGDRFYYE---NPGVFSRRQLVEIR 955

  Fly   740 KTSLAAIICRNSDGITRVREHVMQRLRDGGNPH-VDCQDLEGFHFNFEPWSE 790
            |:||:.|||.|::.|:.:..   :..|.|   | |.|..:.....|  .|.:
Worm   956 KSSLSRIICDNTNTISTIPR---EAFRVG---HMVPCSQIPSMDLN--QWRD 999

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	180/555 (32%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	138/397 (35%)
skpo-3	NP_495511.1	ShKT	41..75	CDD:214586
skpo-3	NP_495511.1	An_peroxidase	464..978	CDD:376988	181/565 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920