Protein Alignment cd and Duox

DIOPT Version :10

• Sequence 1: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Sequence 2: XP_319115.5
• Gene: Duox / 1279399
• VectorBaseID: AGAMI1_000295
• Length: 1511
• Species: Anopheles gambiae
• Alignment Length: 613
• Identity: 179/613 - (29%)
• Similarity: 280/613 - (45%)
• Gaps: 107/613 - (17%)

  Fly   219 RRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPRVSHHGRLPPARQVSLKIHRSSYETD- 282
            :|..|..||..|| .:||......|.....|:||:.....|:.   |..|::|....|.   ||
Mosquito    43 QRYDGWYNNLAHP-DWGAVDNHLTRKAPSAYSDGVYVMAGSNR---PSPRKLSRLFMRG---TDG 100

  Fly   283 ----SNFTVMLAVFGQFMDHDITATSLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYYKQY 343
                .|.|.:||.|||.:.::|    :..|:.|    |.:...|.:..:|       |:.|.::
Mosquito   101 LPSMENRTALLAFFGQVVTNEI----VMASESG----CPIEMHRIEIEKC-------DEMYDRE- 149

  Fly   344 NISC-----MNFVRSA-PAPTGRF--GPRMQLNQATAFIDASVVYGNLEQRQNQLRSFINGSLRM 400
               |     :.|.|:| ...||:.  .||.|:||.||:||.|.:|...|...|.:|||.:|:|
Mosquito   150 ---CRGDRYIPFHRAAYDRNTGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFQDGAL-- 209

  Fly   401 FVTD-------DGRQLLPISSNPADGCNR-VQMTRLGKYCFESGDDRANENLLLTSMHLLWARHH 457
             :||       .....:|:.:||.....| :...||    :..||.|.|:|..|.|..:|:.|.|
Mosquito   210 -LTDKQGTMPVKNTMRVPLFNNPVPHVMRMLSPERL----YLLGDPRTNQNPALLSFAILFLRWH 269

  Fly   458 NYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPD 522
            |.:|::::.|:..|.||.::|.||:::.|.:.:|...|:||..|.|.|....|
Mosquito   270 NVVAKRVRRQHRDWSDEEIFQRARRVVIASLQNIVAYEYLPAFLDKEIPPYDG------------ 322

  Fly   523 TYDPEVDPSIANCFAAAAFRFAHTLL-PGLF------NISRDNSTPEAIELHKMLFNPFSLWAEH 580
             |..:..|.:::.|.||||||.|:|: ||||      |..|.|....|:.|....:|...:....
Mosquito   323 -YKADTHPGVSHMFQAAAFRFGHSLIPPGLFRRDGQCNFRRTNMDFPALRLCSTWWNSNDVLDNT 386

  Fly   581 GIDHALMTAANTPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFR 645
            .::..:|..|:....:.|.....:|..||| |..|    ....||.:|||.||||:|:|.|...|
Mosquito   387 PVEEFIMGMASQIAEKEDPLLCSDVRDKLF-GPME----FTRRDLGALNIMRGRDNGLPDYNTAR 446

  Fly   646 RHCRLPTVDTWEEMSQAI---DNATLDSIRQIYESPQD-VDVYTGALSEPPLDGAIFGPLLSCMV 706
            ...|||...:|.:::.|:   ....||.:.:.|::..| ||||.|.:.|.  ||.. |.|.|.::
Mosquito   447 AAYRLPKKKSWRDINPAVFERQPELLDLLIKTYDNQLDNVDVYVGGMLES--DGRP-GELFSAVI 508

  Fly   707 SDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNP 771
            .|||.|::..|..|:|.: ....|||.::|||.|.:|..||..::|
Mosquito   509 IDQFTRIRDADRFWFENE-DNGIFTKEEIAEIRKFTLWDIIVNSTD------------------- 553

  Fly   772 HVDCQDLEGFHFNFEPWSEKQQPQDLHS 799
             ::..:::...|:::......||:.|::
Mosquito   554 -IEADEIQRDVFHWKQGDPCPQPEQLNA 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..762	CDD:460804	175/574 (30%)
Duox	XP_319115.5	None