DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment cd and epx

DIOPT Version :9

Sequence 1:	NP_651081.1	Gene:	cd / 42681	FlyBaseID:	FBgn0263986	Length:	830	Species:	Drosophila melanogaster
Sequence 2:	XP_021326443.1	Gene:	epx / 100331172	ZFINID:	ZDB-GENE-130425-2	Length:	828	Species:	Danio rerio

Alignment Length:	727	Identity:	232/727 - (31%)
Similarity:	366/727 - (50%)	Gaps:	112/727 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 LEEG-LQPNEVNTPSFRHYRSLSTNPEARKLARRG-YVENQATIDIAKRFNYT---KQPGRSNI- 194
            |.|| ::||:: ...|:     .|.|:.:...|.. :::|  |:::.:...||   .:|..|.:
Zfish     3 LSEGSVRPNDL-LALFK-----QTGPKTKAHIRAAEFLDN--TVELIREMVYTHSMDKPDLSELL 59

  Fly   195 ------------GWGPKIVLPDPTVLRLECDFNARYRRSTGVCNN----KQHPRTYGASMVPYRR 243
                        |...::..|   |.:.:| .:.|||..||.|||    :::|: :||:..||.|
Zfish    60 SAEDMETILQATGCSAEMKRP---VCKSDC-LSKRYRTITGHCNNSYFDRENPQ-WGAANTPYAR 119

  Fly   244 MVSPDYADGIAAPR------VSHHGRLPPARQVSL-KIHRSSYET----------DSNFTVMLAV 291
            .:||.|.|...|||      ..|:..|||.|..:: .:.|.|.|.          |.:.:.:|..
Zfish   120 WLSPQYEDPRGAPRGWSPQHTYHNHTLPPVRLTAVPNVRRVSQEVLYTQNGNITLDGSLSHLLVE 184

  Fly   292 FGQFMDHDITAT--SLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYYKQYNISCMNFVRSA 354
            :||::|||:|.|  |.:|:......||  ..|......|:|:.|...||  :.:..|||.|.|||
Zfish   185 WGQWIDHDLTLTPQSPSTAAFRTRADC--TRTCSTDTPCFPIQIPLSDP--RSHTQSCMAFFRSA 245

  Fly   355 PAPTGRFGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFING----SLRMFVTDDGRQLLPI--- 412
            |:.:...|.|.|||..|||:|:|:|||:.:.....||:..:.    ::..|.:|.|...:|.
Zfish   246 PSCSSPLGQREQLNAITAFVDSSMVYGSSDALALSLRNLSSPLGLLAVNQFHSDQGFDFMPFLNR 310

  Fly   413 SSNPADGC---------------NRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNYLAR 462
            :....|.|               |.:.|.. ..:||::||.||||:|.:.::|.|:.|.||.||:
Zfish   311 TQPQLDPCGPRQHSDHTTAPQQNNNISMGN-ASFCFQAGDSRANEHLGMIALHTLFLREHNRLAK 374

  Fly   463 QLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTYDPE 527
            :|...||||..:.|||||||||||....:|::.:||.:||::.::.  |:||...      |||.
Zfish   375 ELHRINPHWSPDTLYQEARKILGAVHQILTWDHYLPHVLGRSANQI--LMPAYKG------YDPA 431

  Fly   528 VDPSIANCFAAAAFRFAH-TLLPGLFNISRD---NSTPEAIELHKMLFNPFSLWAEHGIDHALMT 588
            .||||:|.|:.||||||| |:.|.:..:..|   :....|:.||..||..:.:..|.|||..|..
Zfish   432 ADPSISNIFSTAAFRFAHVTVHPVVNRLGPDYRLSPAHPALPLHHSLFASWRVVKEGGIDPVLRG 496

  Fly   589 AANTP--VMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLP 651
            ...:|  :...|:....|:|::||:  |:..:|   |||.:||:|||||||:..|.|:|..|.||
Zfish   497 LLVSPAKLQTADQMMVEELTERLFQ--AQGGLP---LDLAALNLQRGRDHGLQGYSVWRELCGLP 556

  Fly   652 TVDTWEEMSQAIDNATL-DSIRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKL 715
            .......:|..:.|..| ..:..:|...:::||:.||::||.|.|...||||:|:::.||..|:.
Zfish   557 APVNESALSGILGNTALARKLLDLYGVAENIDVWVGAIAEPALPGGRVGPLLACLIARQFRGLRD 621

  Fly   716 GDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPH--VDCQDL 778
            ||..|::.:   ..|:..|...:..|||:.|||.|    |.:::..:....:...|.  :.|.::
Zfish   622 GDRFWWQNE---GVFSSGQRDALRSTSLSRIICEN----THIQQVPLDPFTNTMRPEELLSCSNI 679

  Fly   779 EGFHFNFEPWSE 790
            :  .||...|:|
Zfish   680 Q--LFNLSAWTE 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cd	NP_651081.1	An_peroxidase	218..755	CDD:281139	205/588 (35%)
cd	NP_651081.1	peroxinectin_like	364..750	CDD:188655	148/414 (36%)
epx	XP_021326443.1	An_peroxidase_like	111..689	CDD:326323	203/604 (34%)
		CCP	<711..747	CDD:153056
		EGF_CA	748..>775	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920