Protein Alignment wake and LOC100535772

DIOPT Version :9

• Sequence 1: NP_001287469.1
• Gene: wake / 42676
• FlyBaseID: FBgn0266418
• Length: 1648
• Species: Drosophila melanogaster
• Sequence 2: XP_021326079.1
• Gene: LOC100535772 / 100535772
• -ID: -
• Length: 1342
• Species: Danio rerio
• Alignment Length: 1687
• Identity: 442/1687 - (26%)
• Similarity: 701/1687 - (41%)
• Gaps: 443/1687 - (26%)

  Fly    36 KRQQRKERQAQQSAAAAASGAGGAGGAGGGGGGSGS------QSRPGSRKLPPPLL-RSRTLPAI 93
            :|:.|.|..|::.|..                 |||      ::|...|:|..||| :|||||:|
Zfish    13 RRRSRDELMARRDARR-----------------SGSYCCTVAEARSLERRLQRPLLAKSRTLPSI 60

  Fly    94 IVPGLPVVSLHTDKQTFQLDERLLGSKSRSGSASGHRWSLLTRATNSSSMCSNNNPASSSSSSSN 158
              |..|..                                 .|...:.|.|.........||...
Zfish    61 --PQSPAA---------------------------------VRVQQTESDCERQQRPRVPSSPGG 90

  Fly   159 NNNNLHMANNNNTLMVKSLNLP--------KDDSNLVYRRKSSGSTPHQHQNAHHHHQQHHHLQQ 215
                           :::..:|        :|:|.......:....|.......|..::..:|::
Zfish    91 ---------------LEACTIPPAGEMWRLEDESEADMAPGAVDLRPRSQSPFSHFRRRAAYLRK 140

  Fly   216 QQQQQQQHQQQQLQQQQMLQHLGDSSLFQLSDDFECHADGSLLLRIPAPHVVAARAYRLAARKRA 280
            .....              .||.||....:..:....||         |.....|.:.|.:..|.
Zfish   141 SISAD--------------DHLVDSEFQSIQTEDRSSAD---------PKAKLKRKFSLGSIDRK 182

  Fly   281 AASSEASTPMTREHTLHEMPLAESACSGSATGSG-TTFTRLAKLLHQSSTLAGRSNLQPPPMADN 344
            .         ||:.               .|.|| ...|:...|..:..:...||....||
Zfish   183 G---------TRQR---------------RTESGIVKLTQRLSLKDKHCSKEDRSLQSRPP---- 219

  Fly   345 AVQSLGRGLGLGLGEEAPRRLSWERRKDSSALQRSASIDSFAEIVFSE---SPRPSLAVTGPGAC 406
                            |.||             ||.|:| :||...::   .|.|.:|.....:|
Zfish   220 ----------------AYRR-------------RSLSVD-WAESKMTQQIPDPHPLIARKYSTSC 254

  Fly   407 ASASGGPSPFSKRPSASSLYSTSTSSSFASQMQAQLNVNYGDSALGSGSATGGPGSGHHHGASGG 471
            :|.          |||:.....:.|..|.:     .|:...|:.|        ||.
Zfish   255 SSP----------PSAARRLYRNLSGKFRT-----ANLVLDDTTL--------PGQ--------- 287

  Fly   472 GNGGSSASSSRRESMLSPSSTRRSKLTRIINALFSAVEHGHLEKARTILES---TDVDVNSINND 533
                |....|.:.:|...:           .|||.||||..|:...::|.:   .::|:|:.|::
Zfish   288 ----SDKEQSHKTTMFQGN-----------EALFEAVEHQELDVVESLLNTFSLEELDLNTPNSE 337

  Fly   534 GLSALDLAVLSNNRSMTRMLLQHGAVEGSQF-SVDTIGTKLNGLLKDAESRIHDLSGPEGLCPPV 597
            ||..||:|:::||..|.::||:.||.|...| |::.....|..|:::||.||.:|
Zfish   338 GLLPLDIAIMTNNVPMAKLLLRAGAKESPHFLSLEGRAAHLASLVQEAEHRIAEL---------- 392

  Fly   598 FASRPSISSIIIGNSSASVTG-----CTGSEVEKQIGIWERRVKGLRRLQLGWDQARPPDAPASV 657
                           .|.|||     ...|..|:|:..||.:::..:|:|.|:..|.||:.|:.|
Zfish   393 ---------------VAQVTGEEPGEREESNRERQLKSWEWKLRLYKRMQTGYTHASPPEPPSDV 442

  Fly   658 VVDVTGDNSISVQILEPF--EGAIGTKFKVQWSTRADFNNVVGESELLEWISFHGTMGAQCHISG 720
            .:.|:...|:.|...||.  ..|:.||::|.||:.:.|:.::||: ::|.::     ..|..|:|
Zfish   443 HLCVSSGTSLRVYFQEPLCHNSAVITKYRVSWSSVSSFSPLLGET-VIEDVT-----QLQYDITG 501

  Fly   721 LTQGRRYFLRAACGNVKGWGTYRTSVPASVVPSTWRDLDNREDRFVGRHRILDNLFTAVRLA-RP 784
            |..|...:::.:..|:|||.:.:.|.||...||:||::|....|..|....|:.|...::.| |.
Zfish   502 LAAGTGCYVQVSAYNMKGWSSPQISEPACATPSSWREVDGLPPRQQGLKEALEQLLGQIKGAHRH 566

  Fly   785 ADVSELTLDPASAQRRNPKKKTTIKQLFSVTTKFQKTLRRGIYFSCIIHCDDKVLVTSEDFPPVI 849
            ....|....|::.::.:..|  :::.||..|:||.|.|:||:|.:||.:.|:.||||.||..||:
Zfish   567 CACHEQIKAPSNTRKHSVSK--SLRHLFQPTSKFVKNLKRGLYLACIFYQDENVLVTPEDQLPVV 629

  Fly   850 EVDESYPSALHMDYYWLMKVACTWEDVKSLRSDMERNLTSA-------VHFRTKLLSAVCQMQSA 907
            |||:|: |....|..|..||...||::    |.|::.::.|       :..|.|||.|..|:|:.
Zfish   630 EVDDSF-SCHAQDLLWFTKVCHLWEEL----SWMQQCISPAHACSSCTLQTRLKLLQAAAQLQAL 689

  Fly   908 LGITDLGQLYYKPLRDAQGTVVLTCVQSVKSQKAVSILNS-RWVPVSKLQ---KKLGALHEDYTI 968
            ||..||||:|::|::|..|..||..   :|...|.:.|.. ||:||||.|   :...:..|:.:.
Zfish   690 LGTVDLGQVYFEPIKDKHGNAVLVL---LKDMSACAPLEGLRWIPVSKFQLQRRSSSSSSEEPSA 751

  Fly   969 NELLISSIGDQLHYQQAALQRLEPGLYLGYLKMQCSIDQIQVVVPVKTPNVLPHCKVRENSHITA 1033
            .|.|:|::.::|.|.:.:.:.|.|||||||||:..|:|||:|:|..|.||||.|.|:|:|.|::.
Zfish   752 LETLLSTLHEKLSYHRRSRKCLPPGLYLGYLKLYTSVDQIRVLVSHKHPNVLCHVKIRDNGHVSR 816

  Fly  1034 EEWQVLHRYSSDPLRLPLDFSAQGGDGASGATATTEVQRLFLYDLTNAMHKLFASMNIKIADATT 1098
            ||||.|...:|      |:.||:..:.|..|.     .||.| ||..|..:|.|.:||....|..
Zfish   817 EEWQWLQSLTS------LEDSAKVCEDAQSAP-----HRLLL-DLRTAAKELLAYVNIPNQQAQD 869

  Fly  1099 HRLYDVEVIEHSPDISFLVVCPSAESSCAVPGQSELLLQRDDLASLSIQAFEMIHLRTYQPAIIQ 1163
            .|:|..||:|....:|||::.|..|..|:.|||:.|...|....:|.:|.||::|..:|.|:.|.
Zfish   870 FRVYVKEVVELGEGVSFLLLLPPCEEVCSPPGQNHLCSPRSSFFTLPLQIFELVHFESYSPSFIS 934

  Fly  1164 KYARLSCILELDTALATHSLREAFSSSELQAAKERLATLQELSASLTIVWKSVRWLMDVVAYARN 1228
            .|.::|.:|.|::.::..|||||||.|||.:||::...::|....:..:|:..||:: ::..||.
Zfish   935 LYCQVSALLALESLMSQQSLREAFSESELFSAKQKHQQVEEYLQHMEELWRDARWMV-ILQSARY 998

  Fly  1229 KNAQPSLAMREILDFAQQRQDEAVATSAGGSANKQLLQLPIRESKFSKTGQGRGSWPGPGTSEDQ 1293
            |:....:::..|:||.::...|..|     |.:.|:..||.               |.| :.|:.
Zfish   999 KHQSSGVSLAWIIDFTKETIPEKPA-----STSSQVDFLPS---------------PSP-SPENT 1042

  Fly  1294 SQNKPEHSKSEQNL---------------------ELSAITPVEPASNQVPTQQQQPQQQSQQQQ 1337
            .::...|...|.|.                     ||..:.|...:....|:...|...:|.|..
Zfish  1043 RKHTDSHLSDEDNTSDVFLTTDSSEYSSSVTPSTRELDLLPPSPSSFRSPPSSSSQSSPRSSQPD 1107

  Fly  1338 LLQVSNISEYAGSICSEVSFRKNSGDSMSSTYTSRSFYSAVDSASDGNSTNSVFAIPPSRSDDTL 1402
            :||                           ..:.|...|.:||.         |.:|.
Zfish  1108 VLQ---------------------------PVSRREHISVLDSD---------FILPS------- 1129

  Fly  1403 ADALRHSQAVAAQRKRTSSNIASHTNPLITVHSSSSAPYLAGSSVSLRSGNGAFATDLEHKPLKP 1467
                |..:.:....|||:          :.|.:||                      ||:.|..|
Zfish  1130 ----RQIELLRVTEKRTA----------LCVRTSS----------------------LEYPPTTP 1158

  Fly  1468 ATKAASSANLREGGPY---LKSTLAELRAVGGEEPVASTSKASSMKSLSRQSSEEDSASCSSLNA 1529
             |..|||..:|...|.   |..:..|.|    ..||.:.|:.|.::.||..::......|.|
Zfish  1159 -THTASSNQMRWTRPSSFDLCFSAPEPR----PSPVRTLSEDSGVQRLSDPAAGSPHRQCHS--- 1215

  Fly  1530 EQTSGIIQVYTAYSTGLASGTSLKIHVTPKTTAREVINLVVKQLN---------------MAVVL 1579
                 .::||..|.|||...||:|:.|||:|.|.|::.|||:::|               .|...
Zfish  1216 -----TLRVYPQYRTGLPKDTSVKLRVTPETCAAELVRLVVQEMNAVCRHLQKATHQCSCAADQC 1275

  Fly  1580 KGNNGPIYGPEMLENFCLVAVIGARERCLRDDFKPLQLQNPWKKGRLYVRKKHELLAAIEHS 1641
            ..::..:|..|.|::|.||.::..||:.|:|||.||.|||||.:|:|.||.|.....|:::|
Zfish  1276 VPSDVCVYSGEQLQHFGLVLLVEGREKWLQDDFCPLTLQNPWTRGKLCVRFKEYSPLALQYS 1337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wake	NP_001287469.1	ANK	502..>558	CDD:238125	22/58 (38%)
		Ank_4	502..554	CDD:290365	20/54 (37%)
		ANK repeat	503..531	CDD:293786	11/30 (37%)
		ANK repeat	533..558	CDD:293786	10/24 (42%)
		FN3	651..748	CDD:238020	28/98 (29%)
		UBQ	1533..1631	CDD:294102	43/112 (38%)
LOC100535772	XP_021326079.1	ANK	301..>379	CDD:238125	27/88 (31%)
		ANK repeat	301..335	CDD:293786	11/44 (25%)
		ANK repeat	337..370	CDD:293786	14/32 (44%)
		FN3	436..521	CDD:214495	26/90 (29%)
		TGS	1214..1326	CDD:330245	43/119 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1305469at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010