Protein Alignment loco and SLC9A3R1

DIOPT Version :9

• Sequence 1: NP_732773.1
• Gene: loco / 42672
• FlyBaseID: FBgn0020278
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_004243.1
• Gene: SLC9A3R1 / 9368
• HGNCID: 11075
• Length: 358
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 91/441 - (20%)
• Similarity: 146/441 - (33%)
• Gaps: 168/441 - (38%)

  Fly    74 VRRGYNGFGFTISGQ-----QPCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLI 133
            :.:|.||:||.:.|:     |..||  :...||||:|||.:||.|:.|||.||.|..|:.||..|
Human    17 LEKGPNGYGFHLHGEKGKLGQYIRL--VEPGSPAEKAGLLAGDRLVEVNGENVEKETHQQVVSRI 79

  Fly   134 GNSFGSIRMQIAENYYSDSSDEENAHATLRGQLLAASLRHKPRFLHHKAKLHRLRNSPQKKLNPP 198
            ..:..::|:.:.:    ..:||:.       |.|...:|.         :|.|.:.:| .:..||
Human    80 RAALNAVRLLVVD----PETDEQL-------QKLGVQVRE---------ELLRAQEAP-GQAEPP 123

  Fly   199 EAV---------EPHKS-KSSPDHPTLKPVLEDPPLTANLSKAADVANVSAMVRAVGSAALECRV 253
            .|.         ||.:: ||.|:...|:|
Human   124 AAAEVQGAGNENEPREADKSHPEQRELRP------------------------------------ 152

  Fly   254 IVGYLGTIEMPKQISHSSKLQTVRSCIRK---------LRQEKRQPTIVLMCITPDSLSLQSSSG 309
                                   |.|..|         |..:|.:|...:..:.|||   .:.:.
Human   153 -----------------------RLCTMKKGPSGYGFNLHSDKSKPGQFIRSVDPDS---PAEAS 191

  Fly   310 GVLATYSSARLNFVSSSSESENRFFGLVTSAVHNTQIEEEYEPSAGSAAAAGH----ISISHSCH 370
            |:.|......:|.|.    .|.:..|.|.||:.                |.|.    :.:.....
Human   192 GLRAQDRIVEVNGVC----MEGKQHGDVVSAIR----------------AGGDETKLLVVDRETD 236

  Fly   371 VFVIDTKLIEHAQHLQ-------RAHEFRLQCTRDPISNLCLEFPNNSEYVVNLVRSMYTMRILP 428
            .|....::|...:||.       ...|.:.:.:|:.::...||.|.                  |
Human   237 EFFKKCRVIPSQEHLNGPLPVPFTNGEIQKENSREALAEAALESPR------------------P 283

  Fly   429 PASRSHQADYEAGAGAAAAGGAVAAAHSPQPSNHSEISTTTSNSDSGIGFN 479
            ...||..:|         ....:.:..|| |...|...::||:||..:.||
Human   284 ALVRSASSD---------TSEELNSQDSP-PKQDSTAPSSTSSSDPILDFN 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492	30/75 (40%)
		PTB_RGS12	251..391	CDD:269984	24/159 (15%)
		RGS_R12-like	828..941	CDD:188661
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
SLC9A3R1	NP_004243.1	PDZ_signaling	12..91	CDD:238492	30/75 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..192		20/140 (14%)
		PDZ_signaling	152..231	CDD:238492	21/160 (13%)
		EBP50_C	235..358	CDD:312529	23/118 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	277..358		17/76 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900