DRSC/TRiP Functional Genomics Resources

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Protein Alignment loco and PDZD3

DIOPT Version :9

Sequence 1:NP_732773.1 Gene:loco / 42672 FlyBaseID:FBgn0020278 Length:1541 Species:Drosophila melanogaster
Sequence 2:XP_011541302.1 Gene:PDZD3 / 79849 HGNCID:19891 Length:571 Species:Homo sapiens


Alignment Length:130 Identity:35/130 - (26%)
Similarity:53/130 - (40%) Gaps:21/130 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 RTVEVRRGYNGFGFTIS-GQQPCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLI 133
            |...:.:...||||::: |.|......:.:...||:||:..|..|:.|||::|.|..|..:.:.:
Human   222 RLCHIVKDEGGFGFSVTHGNQGPFWLVLSTGGAAERAGVPPGARLLEVNGVSVEKFTHNQLTRKL 286

  Fly   134 GNSFGSIRMQIAENYYSDSSDEENAHATLRGQLLAASLRH------KPRFLHHKAKLHRLRNSPQ 192
            ..|...:.:.:|       ..|........|..|||.|..      |||.||       |...||
Human   287 WQSGQQVTLLVA-------GPEVEEQCRQLGLPLAAPLAEGWALPTKPRCLH-------LEKGPQ 337

  Fly   193  192
            Human   338  337

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
locoNP_732773.1 PDZ_signaling 69..145 CDD:238492 20/75 (27%)
PTB_RGS12 251..391 CDD:269984
RGS_R12-like 828..941 CDD:188661
RGS12_RBD 1073..1145 CDD:176412
RBD 1144..1213 CDD:128731
PDZD3XP_011541302.1 PDZ_signaling 113..193 CDD:238492
PDZ_signaling 221..298 CDD:238492 20/75 (27%)
PDZ 326..411 CDD:214570 8/19 (42%)
PDZ_signaling 466..545 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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