DRSC/TRiP Functional Genomics Resources

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Protein Alignment loco and Pdzph1

DIOPT Version :9

Sequence 1:NP_732773.1 Gene:loco / 42672 FlyBaseID:FBgn0020278 Length:1541 Species:Drosophila melanogaster
Sequence 2:NP_081277.1 Gene:Pdzph1 / 69239 MGIID:1916489 Length:1238 Species:Mus musculus


Alignment Length:323 Identity:74/323 - (22%)
Similarity:120/323 - (37%) Gaps:88/323 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 RTVEVRRGYNGF--GFTISGQQPCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQL 132
            |||.:.:|...:  ||.|...:|..::.:.::|.||:|||:.||.::||||..|:.:.|...|.|
Mouse   904 RTVRLFKGTGDYPWGFRIQFSKPIVVTEVDTNSAAEEAGLQIGDVVLSVNGTEVTSVEHAEAVHL 968

  Fly   133 IGNSFGSIRMQIAENYYSDSSDEENA-HATLRGQLLAAS--------------LRHKPRFLHHKA 182
            .......:.|.:|    ||.|...|. ..|.||.|...:              |:|....|::| 
Mouse   969 AKKGLDILTMVVA----SDISRCPNTPWPTCRGYLHKRTHSGFVKGWRKRWFVLKHDGFLLYYK- 1028

  Fly   183 KLHRLRNSPQKKLNPPEAVEPHKSKSSPDHPTLKPVLED--PPLTANLSKAADVAN------VSA 239
              ||   ..:.|..|.:.::...::...|:...||.:.:  |...:.:......:|      :.|
Mouse  1029 --HR---KDEGKWPPLDMIKLEGAEVDIDNSLGKPFVFNCMPQSGSRILCLCATSNQEMKRWLEA 1088

  Fly   240 MVRA--------------VGSAALECRVIVGYLGTIEMPKQISHSSKLQTVRSCIRKLRQEKRQP 290
            |.||              |.:::|.             |..|.|.       .|:..|.|.:|..
Mouse  1089 MQRAARPVHQNHVWEDVTVHNSSLP-------------PLAIKHP-------ECLGLLHQLERST 1133

  Fly   291 TIVLM--CITPDSL--------SLQSSSGGVLATYSSAR---------LNFVSSSSESENRFF 334
            .:.:.  ||..|..        |.|:|.|..|..||.:.         :....||.|.:..:|
Mouse  1134 DVWIQHYCILKDGCLYFYASIRSTQASGGLYLQGYSVSEQTHGFEQPVIELKPSSEEFKTFYF 1196

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
locoNP_732773.1 PDZ_signaling 69..145 CDD:238492 25/76 (33%)
PTB_RGS12 251..391 CDD:269984 21/103 (20%)
RGS_R12-like 828..941 CDD:188661
RGS12_RBD 1073..1145 CDD:176412
RBD 1144..1213 CDD:128731
Pdzph1NP_081277.1 PDZ_signaling 903..981 CDD:238492 25/76 (33%)
PH-like 986..1093 CDD:302622 21/112 (19%)
PH 993..1094 CDD:278594 21/106 (20%)
PH-like 1123..1215 CDD:302622 17/74 (23%)
PH 1125..1216 CDD:278594 17/72 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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