DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loco and Rgs10

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	XP_006508202.1	Gene:	Rgs10 / 67865	MGIID:	1915115	Length:	185	Species:	Mus musculus

Alignment Length:	161	Identity:	65/161 - (40%)
Similarity:	94/161 - (58%)	Gaps:	5/161 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   797 TTPAPPSAITASVAAEGAA----QDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFW 857
            |..||.|.:......:|::    |.....:.||.|.|.:|:|..|:|.|.||||||||.||:.||
Mouse    11 TAEAPDSVLRDIHDGDGSSSSGHQSLKSTAKWASSLENLLEDPEGVQRFREFLKKEFSEENVLFW 75

  Fly   858 TACERYRLLESEADRVAQAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIF 922
            .|||.::..|.......:|:||:...|:|.:|..|||:.|:| |||:.|.:..|.:|...|.|||
Mouse    76 LACEDFKKTEDRKQMQEKAKEIYMTFLSNKASSQVNVEGQSR-LTEKILEEPHPLMFQKLQDQIF 139

  Fly   923 SLMKFDSYQRFIRSDLYKSCVEAEQKNQPLP 953
            :|||:|||.||::|||:......|::.:..|
Mouse   140 NLMKYDSYSRFLKSDLFLKPKRTEEEEEEPP 170

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661	54/112 (48%)
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
Rgs10	XP_006508202.1	RGS_RGS10	46..158	CDD:188695	54/112 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850627
Domainoid	1	1.000	117	1.000	Domainoid score	I5880
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D144440at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750