DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loco and Rgs19

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_067693.1	Gene:	Rgs19 / 59293	RGDID:	629471	Length:	216	Species:	Rattus norvegicus

Alignment Length:	161	Identity:	54/161 - (33%)
Similarity:	82/161 - (50%)	Gaps:	23/161 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   784 QHQLSLLQVPKVLTTPAPPSAITASVAAEGAAQDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKE 848
            :.:|..|...:|.|.|:|...                 .|||.||::::....|...|..||:.|
  Rat    64 ESKLQPLPSCEVCTPPSPEEV-----------------QSWAQSFDKLMHSPTGRSVFRAFLRTE 111

  Fly   849 FSAENIYFWTACERYRLLESEADRVA---QAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAA 910
            :|.||:.||.|||.   |::||||..   :||.|:..:::..|...|::||:.|.....|:.:.:
  Rat   112 YSEENMLFWLACEE---LKTEADRHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINRKMQEPS 173

  Fly   911 PDIFAPAQKQIFSLMKFDSYQRFIRSDLYKS 941
            |..|..||.||::||..|||.||:.|..|:|
  Rat   174 PHTFDDAQLQIYTLMHRDSYPRFLTSPTYRS 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661	43/115 (37%)
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
Rgs19	NP_067693.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		RGS	87..204	CDD:413378	46/119 (39%)
		Interaction with GIPC	207..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810