DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loco and rgs5a

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_956256.1	Gene:	rgs5a / 573765	ZFINID:	ZDB-GENE-030131-7570	Length:	182	Species:	Danio rerio

Alignment Length:	133	Identity:	45/133 - (33%)
Similarity:	74/133 - (55%)	Gaps:	7/133 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   812 EGAAQDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFWTACERYRLLESEADRVAQA 876
            |.|||       |..|.:::|.::.|:.||..||:.|||.|||.||.|||.::..::......:|
Zfish    57 EEAAQ-------WRESLDKVLSNSYGLATFKSFLRSEFSEENIEFWEACEDFKKTKNPLKMATKA 114

  Fly   877 REIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSLMKFDSYQRFIRSDLYKS 941
            ::|:...:.......||:|...:.:|...|.|.:...|..||.:|::||:.||:.||:|||.|:.
Zfish   115 KKIYEDFIQTGGPKEVNIDHFTKDVTLRNLVDLSSSTFELAQSRIYTLMEKDSFGRFLRSDQYQE 179

  Fly   942 CVE 944
            .::
Zfish   180 LLK 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661	39/112 (35%)
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
rgs5a	NP_956256.1	RGS	66..179	CDD:295367	39/112 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810