DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loco and lnx1

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	XP_005160562.1	Gene:	lnx1 / 561226	ZFINID:	ZDB-GENE-030131-9439	Length:	769	Species:	Danio rerio

Alignment Length:	85	Identity:	27/85 - (31%)
Similarity:	43/85 - (50%)	Gaps:	11/85 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 RTVEVRRGYNG-FGFTISGQQPCRLSC--------IISSSPAEQAG-LRSGDFLISVNGLNVSKL 124
            :.:.:||..:| .||:|.|.|. .|:|        |:..:||...| :|.||.|:.|||.:...:
Zfish   678 KDIVLRRSTSGSLGFSIVGGQE-ELNCNQSFFIRSIVEGTPAYNDGRIRCGDILLEVNGKSTWGM 741

  Fly   125 PHETVVQLIGNSFGSIRMQI 144
            .|..:|:|:....|.|.:.|
Zfish   742 THTALVRLLKELRGRITLTI 761

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492	27/85 (32%)
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
lnx1	XP_005160562.1	RING	57..93	CDD:214546
		PDZ_signaling	297..381	CDD:238492
		PDZ_signaling	411..491	CDD:238492
		PDZ_signaling	536..621	CDD:238492
		DegQ	<548..621	CDD:223343
		PDZ_signaling	678..762	CDD:238492	27/85 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900