DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment loco and rgs1

DIOPT Version :9

Sequence 1:NP_732773.1 Gene:loco / 42672 FlyBaseID:FBgn0020278 Length:1541 Species:Drosophila melanogaster
Sequence 2:XP_021324130.1 Gene:rgs1 / 556179 ZFINID:ZDB-GENE-070705-145 Length:171 Species:Danio rerio


Alignment Length:154 Identity:56/154 - (36%)
Similarity:82/154 - (53%) Gaps:8/154 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   801 PPSAITASVAAEGAAQDHGCP------SSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFWTA 859
            |||  .|...||..|...|..      .||..|.|::|...||...|.:|||.|:|.|||.||.|
Zfish    19 PPS--EAETHAEDTADRDGHKEPVDDVDSWGESIEKLLSCKAGQAAFQDFLKSEYSEENILFWLA 81

  Fly   860 CERYRLLESEADRVAQAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSL 924
            ||.|:.:.:|.:.::.|.:|:.:.:...:...||:||..|:.....:::.....|..|||.||||
Zfish    82 CEEYKKVTNEPEMISMANQIYTEFVQTEAPRQVNIDSGTRTNITNSISEPTRSSFDTAQKMIFSL 146

  Fly   925 MKFDSYQRFIRSDLYKSCVEAEQK 948
            |..|.|.||::||:|:|.::...|
Zfish   147 MTRDCYPRFLKSDIYQSILQKHGK 170

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
locoNP_732773.1 PDZ_signaling 69..145 CDD:238492
PTB_RGS12 251..391 CDD:269984
RGS_R12-like 828..941 CDD:188661 43/112 (38%)
RGS12_RBD 1073..1145 CDD:176412
RBD 1144..1213 CDD:128731
rgs1XP_021324130.1 RGS 50..161 CDD:321993 42/110 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3589
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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