DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment loco and Rgs1

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	XP_006250036.1	Gene:	Rgs1 / 54289	RGDID:	3561	Length:	209	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	65/216 - (30%)
Similarity:	106/216 - (49%)	Gaps:	35/216 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   738 SDKVAKE-QQQLGQSSPVRRTASMNASDNDMYIKTLM--LDSDLKSSRSQHQLSLLQVPKVLTTP 799
            |.|.:|| ...|...:..::.......|...|:::::  |:|.:|||:|:..||
  Rat    22 SPKDSKEPSHSLLDDNKQKKRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDILS----------- 75

  Fly   800 APPSAITASVAAEGAAQDHGCPSSWAGSFERMLQDAAGMQTFSEFLKKEFSAENIYFWTACERYR 864
                       ||...|       |:.|.|::|.:..|...|.:|||.|||.|||.||.|||.|:
  Rat    76 -----------AEEVMQ-------WSQSLEKLLANQMGQNVFGKFLKSEFSEENIEFWLACEDYK 122

  Fly   865 LLESEADRV-AQAREIFAKHLANNSSDPVNVDSQARSLTEEKLADAAPDIFAPAQKQIFSLMKFD 928
              ::|.|.: .:|..|:...:.:::...:|:|...|..|.:|:....|..|..|||.|::||:.|
  Rat   123 --KTETDLLHNKAEHIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTCFDEAQKVIYALMEKD 185

  Fly   929 SYQRFIRSDLYKSCVEAEQKN 949
            ||.||::|::|.:.:...|.|
  Rat   186 SYPRFLKSNIYLNLLNDLQAN 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661	43/113 (38%)
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
Rgs1	XP_006250036.1	RGS	86..199	CDD:413378	43/114 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3589
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810