Protein Alignment loco and slc9a3r1a

DIOPT Version :9

• Sequence 1: NP_732773.1
• Gene: loco / 42672
• FlyBaseID: FBgn0020278
• Length: 1541
• Species: Drosophila melanogaster
• Sequence 2: NP_997872.2
• Gene: slc9a3r1a / 327272
• ZFINID: ZDB-GENE-031006-7
• Length: 384
• Species: Danio rerio
• Alignment Length: 442
• Identity: 89/442 - (20%)
• Similarity: 150/442 - (33%)
• Gaps: 121/442 - (27%)

  Fly    74 VRRGYNGFGFTISGQ--QPCR-LSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLIGN 135
            :.:|..|:||.:.|:  :|.: :..:...|||..|||.:||.|..|||.||....|:.||..|.:
Zfish    12 LEKGDTGYGFHLHGEKNKPGQFIRHVEPDSPAAAAGLLAGDKLALVNGENVEDEKHQQVVSRIRD 76

  Fly   136 SFGSIRMQIAENYYSDSSDEENAHATLRGQLLAASLRHKPRFLHHKAKLHRLRNSPQKKLNPPEA 200
            :.|.:.:.:.        :.|.|...|:
Zfish    77 TVGKLELVVL--------NAETAELLLK------------------------------------- 96

  Fly   201 VEPHKSKSSPDHPTLKPVLEDPPLTANLSKAADVANVSAMVRAVGSAALECRVIVGYLGTIEMPK 265
               |..|...::     |.:..|:.|......:|.|        |:::.|...:....|.:.:.:
Zfish    97 ---HNLKCQKEY-----VTDGIPIPAGSEPEDEVKN--------GTSSRESTPVPETNGDMRIDR 145

  Fly   266 QISHSSK-----LQTVRSC-IRK--------LRQEKRQPTIVLMCITPDSLSLQSSSGGVLATYS 316
             :|.|||     |:. |.| |:|        |..||.:|...:..:..||   .:...|:.....
Zfish   146 -LSVSSKDSKNELRP-RLCHIKKGATGYGFNLHTEKTKPGQYIRAVDEDS---PAEKSGLRPQDK 205

  Fly   317 SARLNFVSSSSESENRFFGLVTSAVHNTQIEEEYEPSAGSAAAAGHISISHSCHVFVIDTKLIEH 381
            ..::|.:|                ||..|..|..............:.:......|.:..:::..
Zfish   206 IVQVNGIS----------------VHTMQHSEVVAAIKAGGDETKLLVVDPEADAFFMSCEILPT 254

  Fly   382 AQHL----------QRAHEFRLQCTRDPISNLCLEFPNNSEYVVNLVRSMYTMRILPPASRSHQA 436
            .:||          :.|.|   |.....:..   |.|.....:.:...|..|.....||..|..|
Zfish   255 EEHLTGPLPEPIPRREAEE---QVNGKVVQE---EKPKVEMSLSSSSTSSNTSTSAAPAPASAPA 313

  Fly   437 DYEAGAGAAAAGGAVAAAHSPQPSNHSEISTTTSNSDSGIGFNNDCTNISDR 488
            ...|.|.|:|...|:|||  ||    .::....|::|:|:..|.......:|
Zfish   314 PASAPAPASAPAPAMAAA--PQ----EKVKEKASSADAGLALNMSLQQAKER 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492	25/73 (34%)
		PTB_RGS12	251..391	CDD:269984	27/163 (17%)
		RGS_R12-like	828..941	CDD:188661
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
slc9a3r1a	NP_997872.2	PDZ_signaling	7..86	CDD:238492	25/73 (34%)
		PDZ_signaling	159..238	CDD:238492	17/98 (17%)
		EBP50_C	242..384	CDD:312529	29/130 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900