DRSC/TRiP Functional Genomics Resources

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Protein Alignment loco and Lnx1

DIOPT Version :9

Sequence 1:NP_732773.1 Gene:loco / 42672 FlyBaseID:FBgn0020278 Length:1541 Species:Drosophila melanogaster
Sequence 2:NP_001153049.1 Gene:Lnx1 / 16924 MGIID:1278335 Length:728 Species:Mus musculus


Alignment Length:130 Identity:40/130 - (30%)
Similarity:59/130 - (45%) Gaps:15/130 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 AAEDASPAANSGPAPISTSTTPSGSNSQQHQRRRKKRANYNYNGIRTVEVRRGYNG-FGFTI--- 85
            |.||.||||...    :.:.||.|..|.... ...:...|..| .:.|.:||...| .||.|   
Mouse   598 AQEDCSPAALDS----NHNVTPPGDWSPSWV-MWLELPQYLCN-CKDVILRRNTAGSLGFCIVGG 656

  Fly    86 ----SGQQPCRLSCIISSSPAEQAG-LRSGDFLISVNGLNVSKLPHETVVQLIGNSFGSIRMQIA 145
                ||.:|..:..|:..:||...| :|.||.|::|||.:.|.:.|..:.:::....|.|.:.||
Mouse   657 YEEYSGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARMLKELKGRITLTIA 721

  Fly   146  145
            Mouse   722  721

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
locoNP_732773.1 PDZ_signaling 69..145 CDD:238492 25/84 (30%)
PTB_RGS12 251..391 CDD:269984
RGS_R12-like 828..941 CDD:188661
RGS12_RBD 1073..1145 CDD:176412
RBD 1144..1213 CDD:128731
Lnx1NP_001153049.1 mRING-HC-C3HC3D_LNX1 42..83 CDD:319693
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 185..220
NPXY motif 185..188
Interaction with MAGEB18. /evidence=ECO:0000250 186..244
PDZ_signaling 276..360 CDD:238492
PDZ_signaling 384..464 CDD:238492
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 481..500
PDZ_signaling 506..589 CDD:238492
PDZ_signaling 637..721 CDD:238492 25/83 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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