DRSC/TRiP Functional Genomics Resources

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Protein Alignment loco and rgs3

DIOPT Version :9

Sequence 1:NP_732773.1 Gene:loco / 42672 FlyBaseID:FBgn0020278 Length:1541 Species:Drosophila melanogaster
Sequence 2:XP_002941346.1 Gene:rgs3 / 100486204 XenbaseID:XB-GENE-5900212 Length:330 Species:Xenopus tropicalis


Alignment Length:427 Identity:103/427 - (24%)
Similarity:157/427 - (36%) Gaps:134/427 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   525 PDNRLTVRAMPDHSALLRSPPASSSLRRPNLLASFNLIQSPATNLTSTRSCDDVLNLFVDDSPRT 589
            |||       |.|...:       ::|||:          |:|:.|::.....||.:......|:
 Frog    19 PDN-------PQHWKRV-------AIRRPH----------PSTDSTTSSHPVPVLPVPEVRVERS 59

  Fly   590 LAAVASMDDISLHSAAPSLDEGHTFAHPACVPRKMRRSLALETPTTPHKLSAQVFGQPGSRHSLG 654
            .:|.        |.|..|.:|....|....||..:.|     |.:..|..|.            |
 Frog    60 FSAG--------HLACDSDEEEAKEAETLRVPLAIWR-----TRSESHLDSG------------G 99

  Fly   655 FEAIDSVQSSVSGACMDQTMDTWA--SLQNLHKSHKDRTSMSASSSSHCLLEATNS--------E 709
            .||:...:.|.||         |:  |.:.|.|  |.|.:...::..|.|...|.|        |
 Frog   100 QEALGQKEKSASG---------WSLPSPKTLRK--KRRAAKVTAAKQHLLSFFTGSLKPLPSSGE 153

  Fly   710 PDLGNRALPANASPFRRAWGQSSFRTPRSDKVAKEQQQLGQSSPVRRTASMNASDNDMYIKTLML 774
            .|:|:..                       ::.|.|:.                           
 Frog   154 TDIGSLC-----------------------EIDKGQRH--------------------------- 168

  Fly   775 DSDLKSSRSQHQLSLLQVPKVLTTPAPPSAITASVAAEGAAQDHGCPSSWAGSFERMLQDAAGMQ 839
                |....:|:.|.|.:.::.|:       .:|.....:..|   .:||..|.|.:|....|..
 Frog   169 ----KKKEQKHKKSHLSLFRLWTS-------HSSNIMRPSIDD---VTSWGKSLENLLSHTYGRA 219

  Fly   840 TFSEFLKKEFSAENIYFWTACERYRLLESEADRVAQAREIFAKHLANNSSDPVNVDSQARSLTEE 904
            .|..||:.|||.||:.||.|||.|:.........::||:|:..::|..|...||:|:..|.:||.
 Frog   220 LFRVFLQSEFSDENLDFWLACEEYKDTHPNFILHSRARKIYQLYIALQSPKEVNLDASTREMTEH 284

  Fly   905 KLADAAPDIFAPAQKQIFSLMKFDSYQRFIRSDLYKS 941
            .|.......|..||::|:.||:.|||.||:|||||:|
 Frog   285 NLLIPTRTTFDEAQRRIYGLMERDSYPRFLRSDLYQS 321

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
locoNP_732773.1 PDZ_signaling 69..145 CDD:238492
PTB_RGS12 251..391 CDD:269984
RGS_R12-like 828..941 CDD:188661 45/112 (40%)
RGS12_RBD 1073..1145 CDD:176412
RBD 1144..1213 CDD:128731
rgs3XP_002941346.1 RGS_RGS3 208..321 CDD:188668 45/112 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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