DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment loco and tamalin

DIOPT Version :9

Sequence 1:	NP_732773.1	Gene:	loco / 42672	FlyBaseID:	FBgn0020278	Length:	1541	Species:	Drosophila melanogaster
Sequence 2:	NP_001120354.1	Gene:	tamalin / 100145424	XenbaseID:	XB-GENE-943584	Length:	352	Species:	Xenopus tropicalis

Alignment Length:	233	Identity:	54/233 - (23%)
Similarity:	96/233 - (41%)	Gaps:	52/233 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 AANSGPAPISTSTTPSG----SNSQQHQRRRKKRANYNYNGIRTVEVRRGYNGFGFTISGQQ--- 89
            |.:.|..|.:...:.:|    |.|.::||:           |.|:: :.....|||.|....
Frog    49 AVSGGTLPRTKKGSTAGWKNVSQSSEYQRK-----------ILTLQ-KEDSESFGFEIQTYGLHH 101

  Fly    90 -----------PCRLSCIISSSPAEQAGLRSGDFLISVNGLNVSKLPHETVVQLIGNSFGSIRMQ 143
                       .||:.   ..|||:..||:.||.:..|||||:..:.|..:|:||..|..:||:
Frog   102 QDKNAVEMFTFVCRVQ---DGSPAQLCGLKVGDIIAGVNGLNMDGVRHRDIVELIKVSGNTIRL- 162

  Fly   144 IAENYYSDSSDEENAHATLRGQLLAASLRHKPRFLHHKAKLHRLRNSPQKKL------NPPEAVE 202
              |..|.         :.:|...|.|.:::..:.|:.|.:.:|.....:::|      ..|...:
Frog   163 --ETVYG---------SAIRRAELEARIQYLKQTLYEKWEEYRSLMVQEQRLLHGIVVKDPSVYD 216

  Fly   203 PHKSKSSPDHPTLKPVLEDPPLTANLSKAADVANVSAM 240
            ..:|..|..:.|:....:| |||..|:..:..::.|.:
Frog   217 TLESVRSYIYGTVNTCSKD-PLTGTLAAGSMCSSASCL 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loco	NP_732773.1	PDZ_signaling	69..145	CDD:238492	27/89 (30%)
		PTB_RGS12	251..391	CDD:269984
		RGS_R12-like	828..941	CDD:188661
		RGS12_RBD	1073..1145	CDD:176412
		RBD	1144..1213	CDD:128731
tamalin	NP_001120354.1	PDZ_signaling	78..163	CDD:238492	27/102 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910