DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL45 and Mrpl45

DIOPT Version :9

Sequence 1:	NP_651072.1	Gene:	mRpL45 / 42671	FlyBaseID:	FBgn0263863	Length:	361	Species:	Drosophila melanogaster
Sequence 2:	XP_017170202.1	Gene:	Mrpl45 / 67036	MGIID:	1914286	Length:	364	Species:	Mus musculus

Alignment Length:	321	Identity:	118/321 - (36%)
Similarity:	172/321 - (53%)	Gaps:	67/321 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 TKEEMRSRMKERGVLPPRPWMERPFHISCTGGIFEAYVPPEGDGKKSIISTSGAKQKLEFLEKKS 147
            |::|.....::.|::.|:..:|||.|::||.|||:.|||||||.:.|.:|..|..|:.|.|.|.:
Mouse    52 TEKEFLEYARKAGLVIPQERLERPIHLACTAGIFDPYVPPEGDARMSSLSKEGLTQRTERLRKNA 116

  Fly   148 KSLMAVRKIRSYDENFSSDDFGAEAQDIYIQAHTHMAAKDKYKIREFVSERCYP----------- 201
            .|.:|:||||.:|.||.:.||..:|:||:|:||..:...|..::...|:|.|:|
Mouse   117 ASQLAIRKIREFDANFKTKDFPEKAKDIFIEAHLCLNNSDHDRLHTLVTEHCFPCLKDEISGSTG 181

  Fly   202 -----------------------------------------------EMMHNVKDKTIRWKFLQS 219
                                                           :|:.::|.||:||.|::|
Mouse   182 YRLRPCLHPIPTLKWGERMEALPVGCSIVWAVPHRRGTPVNSSLLPQDMVWDLKYKTVRWGFVES 246

  Fly   220 LEPPRVVHARVTEVITKENQFAQVTVRFHSQQMLAIYDRFGRLMHGSEIITKDVLEYVVFEKHIS 284
            |||.:|||.|.:.::.:.|.:.|||||.|::|.|||||||||||:|.|.:.||||||||||:|:.
Mouse   247 LEPAQVVHVRCSGLVNQSNMYGQVTVRLHTRQTLAIYDRFGRLMYGQEDVPKDVLEYVVFERHLM 311

  Fly   285 NEYGKWRLHDKIIPDWLPAKQPAPITYRLIEDAEEPPKELSAGDAEVKQVDSVGEQSKEQL 345
            |.||.||:|.||:|.|.|.|||...|..:.....:|.:|..         ::.||..|.||
Mouse   312 NPYGSWRMHAKIVPAWAPPKQPILKTLMIPGPQLKPWEEYE---------ETQGEAQKPQL 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL45	NP_651072.1	Tim44	152..297	CDD:282178	75/202 (37%)
Mrpl45	XP_017170202.1	Tim44	119..322	CDD:214950	74/202 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832395
Domainoid	1	1.000	171	1.000	Domainoid score	I3738
eggNOG	1	0.900	-	-		E1_KOG4599
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32647
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3236
Isobase	1	0.950	-	0	Normalized mean entropy	S4578
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005541
OrthoInspector	1	1.000	-	-		oto93058
orthoMCL	1	0.900	-	-		OOG6_104462
Panther	1	1.100	-	-	LDO	PTHR28554
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2761
SonicParanoid	1	1.000	-	-		X4497
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.730