Protein Alignment mRRF2 and MEF1

DIOPT Version :9

• Sequence 1: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_013170.1
• Gene: MEF1 / 850758
• SGDID: S000004059
• Length: 761
• Species: Saccharomyces cerevisiae
• Alignment Length: 714
• Identity: 218/714 - (30%)
• Similarity: 366/714 - (51%)
• Gaps: 73/714 - (10%)

  Fly    31 SKIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTV---TDYLTQERERGITICSSAVT 92
            :|:|||||.||||:||||.|||:|:|..:.:|:.||...:.|   .|.:..|||:||||.|:|..
Yeast    68 NKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATY 132

  Fly    93 FSWN----DHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPR 153
            .||:    ::..||:|||||||||:|||::|..:||.|:|:...:||::|||||..|..::.:||
Yeast   133 CSWDKEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPR 197

  Fly   154 LIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAINDVITLERLSWQQKDLGRSY 218
            :.|:|||||..:|..:.:..|..||:.....:|.|:.:|..:..:.|:|....: :.:.|.|...
Yeast   198 VTFINKMDRMGSDPFRAIEQLNSKLKIPAAAVQIPIGSESSLSGVVDLINRVAI-YNKGDNGEII 261

  Fly   219 RNVKLEPSDDLRLLQEKRNELIDQLSGLDDELADVVISTESFDNVDNALIERALRRATTQQKVVP 283
            ....: |.:...|::|||..||:.|:.:|||:|::.:..:   ......|:.|:||:|..:...|
Yeast   262 EKGPV-PENLKPLMEEKRQLLIETLADVDDEMAEMFLEEK---EPTTQQIKDAIRRSTIARSFTP 322

  Fly   284 VLLGSAYKNVGIQRLMDAVNAYLPAPEE-RNQIYDCFGTEV------------AGKVFKIVHDKQ 335
            ||:|||..|.|||.::||:..|||.|.| .|...|....|.            .|..||:...|.
Yeast   323 VLMGSALANTGIQPVLDAIVDYLPNPSEVLNTALDVSNNEAKVNLVPAVQQPFVGLAFKLEEGKY 387

  Fly   336 RGPLTLVRILRGEIKRGMRLISAR-GQAEVVSKLYEPLADEYREVSAVQSGDVVICAGLKSTVTG 399
             |.||.||:.:|.:::|..:.:.: |:...|::|....:.|..:|..|.||::....|: ...:|
Yeast   388 -GQLTYVRVYQGRLRKGNYITNVKTGKKVKVARLVRMHSSEMEDVDEVGSGEICATFGI-DCASG 450

  Fly   400 DLLTSSQSALKNAQKRYKQSLGNTAAKVEEDDELDESDELFAIDPQIPDAVYFCSIEPPSVSSQT 464
            |..|       :...:|..|                       ...:||||...||.|.|..:..
Yeast   451 DTFT-------DGSVQYSMS-----------------------SMYVPDAVVSLSITPNSKDASN 485

  Fly   465 AMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIAYKETI 529
             ..:||.:.|:|||:.||.:|..:.:|::.||||||::|...|:..||.:|...|..|::|:|:|
Yeast   486 -FSKALNRFQKEDPTFRVKFDPESKETIISGMGELHLEIYVERMRREYNVDCVTGKPQVSYRESI 549

  Fly   530 EAPALTTLSVEKEIAGSKQ--SVSITLEVVKN--QAELFSLDKSPDNLPNLNTLRPRILQVLRKG 590
            ..||....:.:|:..|:.|  .|..||..|.:  :..:|........:|:      :.|....||
Yeast   550 TIPADFDYTHKKQSGGAGQYGRVIGTLSPVDDITKGNIFETAIVGGRIPD------KYLAACGKG 608

  Fly   591 SISALERGPRVGGQVVETQIRLHNATIGRGTAD--SFVMATAAQCVQKLLSTSGTRLLEPIMALQ 653
            .....|:||.:|.:|::.::.:::..|....::  ||..||.:......|..... ::||||.:.
Yeast   609 FEEVCEKGPLIGHRVLDVKMLINDGAIHAVDSNELSFKTATMSAFRDAFLRAQPV-IMEPIMNVS 672

  Fly   654 IVAPSERISGIMADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSALRTISSGTASMTMQ 717
            :.:|:|....::..|::.:|:|.|. ..|.....:.....|:.:.|::::||..:.|....:::
Yeast   673 VTSPNEFQGNVIGLLNKLQAVIQDT-ENGHDEFTLKAECALSTMFGFATSLRASTQGKGEFSLE 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRRF2	NP_732771.2	PRK12739	31..733	CDD:237185	218/714 (31%)
MEF1	NP_013170.1	FusA	68..760	CDD:223556	218/714 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910