DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRRF2 and SCO1

DIOPT Version :9

Sequence 1:	NP_732771.2	Gene:	mRRF2 / 42670	FlyBaseID:	FBgn0051159	Length:	740	Species:	Drosophila melanogaster
Sequence 2:	NP_564801.1	Gene:	SCO1 / 842573	AraportID:	AT1G62750	Length:	783	Species:	Arabidopsis thaliana

Alignment Length:	742	Identity:	262/742 - (35%)
Similarity:	396/742 - (53%)	Gaps:	82/742 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KRSYSSK-IRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTVTDYLTQERERGITICSS 89
            ||:...| .|||||:|||||||||||||:|:|.|:...:||||.|....|::.||:||||||.|:
plant    88 KRAVPLKDYRNIGIMAHIDAGKTTTTERILYYTGRNYKIGEVHEGTATMDWMEQEQERGITITSA 152

  Fly    90 AVTFSWNDHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRL 154
            |.|..|:.||||::|||||:|||:|||::|..:||.:.:.|..||||.|:.|||.||||:.:||:
plant   153 ATTTFWDKHRINIIDTPGHVDFTLEVERALRVLDGAICLFDSVAGVEPQSETVWRQADKYGVPRI 217

  Fly   155 IFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAINDVITLERLSWQQKDLGR--S 217
            .|||||||..|:|.:....:...|..:|:.||.|:..||....:.|::.::.:.|..::||.  |
plant   218 CFVNKMDRLGANFFRTRDMIVTNLGAKPLVLQIPIGAEDVFKGVVDLVRMKAIVWSGEELGAKFS 282

  Fly   218 YRNVKLEPSDDLRLLQEKRNELIDQLSGLDDELADVVISTESFDNVDNALIERALRRATTQQKVV 282
            |.::   |.|...|.||.|..:::.:..||||:.:..:  |..: .|.|.::|.:|:.|...|.|
plant   283 YEDI---PEDLEDLAQEYRAAMMELIVDLDDEVMENYL--EGVE-PDEATVKRLVRKGTITGKFV 341

  Fly   283 PVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQIYDCFGTE-----------------VAGKVFKI 330
            |:|.|||:||.|:|.|:|||..|||:|.|   :....||:                 .||..|||
plant   342 PILCGSAFKNKGVQPLLDAVVDYLPSPVE---VPPMNGTDPENPEITIIRKPDDDEPFAGLAFKI 403

  Fly   331 VHDKQRGPLTLVRILRGEIKRGMRLISA-RGQAEVVSKLYEPLADEYREVSAVQSGDVVICAGLK 394
            :.|...|.||.||:..|:|..|..:::| :|:.|.:.:|.|..|:...:|....:||::..||||
plant   404 MSDPFVGSLTFVRVYSGKISAGSYVLNANKGKKERIGRLLEMHANSREDVKVALTGDIIALAGLK 468

  Fly   395 STVTGDLLTSSQSALKNAQKRYKQSLGNTAAKVEEDDELDESDELFAIDPQIPDAVYFCSIEPPS 459
            .|:||:.|:..::.:                      .|:..|        .||.|...:|||.:
plant   469 DTITGETLSDPENPV----------------------VLERMD--------FPDPVIKVAIEPKT 503

  Fly   460 VSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDVDLGPLQIA 524
            .:....|...|.:|.:||||...|.|....|||:.||||||::||..|:..|:|::.::|..|:.
plant   504 KADIDKMATGLIKLAQEDPSFHFSRDEEMNQTVIEGMGELHLEIIVDRLKREFKVEANVGAPQVN 568

  Fly   525 YKETIEAPALTTLSVEKEIAGSKQSVSITLEVVKNQAEL---FSLDKSPDNLPNLNTLRPRILQV 586
            |:|:|...|....:.:|:..|..|...||:.....:|..   |..:.....:|     |..|..|
plant   569 YRESISKIAEVKYTHKKQSGGQGQFADITVRFEPLEAGSGYEFKSEIKGGAVP-----REYIPGV 628

  Fly   587 LRKGSISALERGPRVGGQVVETQIRLHNATIGRGTADSFVMA---TAAQCVQKLLSTSGTRLLEP 648
            : ||....:..|...|..||:.:..|.:.:.  ...||.|:|   .|....::.:..:|.|:|||
plant   629 M-KGLEECMSTGVLAGFPVVDVRACLVDGSY--HDVDSSVLAFQLAARGAFREGMRKAGPRMLEP 690

  Fly   649 IMALQIVAPSERISGIMADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSALRTISSGTAS 713
            ||.:::|.|.|.:..::.||:.||..||....|....|::....||||:..|.|.||.::.|.||
plant   691 IMRVEVVTPEEHLGDVIGDLNSRRGQINSFGDKPGGLKVVDSLVPLAEMFQYVSTLRGMTKGRAS 755

  Fly   714 MTMQPCGF--------SSMNSVDESLA 732
            .|||...|        :.::|.|:.:|
plant   756 YTMQLAKFDVVPQHIQNQLSSKDQEVA 782

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRRF2	NP_732771.2	PRK12739	31..733	CDD:237185	260/737 (35%)
SCO1	NP_564801.1	PRK00007	89..777	CDD:234569	258/734 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53906
OrthoDB	1	1.010	-	-		D637899at2759
OrthoFinder	1	1.000	-	-		FOG0005123
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR43261
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.030