Protein Alignment mRRF2 and mIF2

DIOPT Version :9

• Sequence 1: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_651621.2
• Gene: mIF2 / 43382
• FlyBaseID: FBgn0039588
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 583
• Identity: 124/583 - (21%)
• Similarity: 215/583 - (36%)
• Gaps: 168/583 - (28%)

  Fly    36 IGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTVTDYLTQERERGIT--ICSSAVTFSWNDH 98
            :.::.|:|.||||..:.:   .|...|.||.               .|||  |.:..||.. |..
  Fly   165 VTVMGHVDHGKTTLLDSL---RGADVAAGEA---------------GGITQHIGAFTVTLE-NGE 210

  Fly    99 RINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVTVWSQADKHKLPRLIFVNKMDRP 163
            |:..||||||..|:....:...|.|.:|:|:....||.|||..|...|.:.::|.::.:||:|:|
  Fly   211 RVTFLDTPGHAAFSAMRARGAVATDIIVLVVAAEDGVMAQTREVIQLAKEAQVPIIVALNKIDKP 275

  Fly   164 DADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAINDVITLERLSWQQKDLGRSYRNVKLEPSDD 228
            :|:.||.    |.:|....:.|:                                     |...|
  Fly   276 EANIEKS----KRELAQMGLALE-------------------------------------EHGGD 299

  Fly   229 LRLLQEKRNELIDQLSGLDDELADVVISTESFDNVDNALIERALRRATTQQKVVPVLLGSAYKNV 293
            ::::.      |..|.|.:.||....:||::                        .|:|......
  Fly   300 VQVIP------ISALKGTNLELLAEAVSTQA------------------------TLMGLKADPT 334

  Fly   294 GIQRLMDAVNAYLPAPEERNQIYDCFGTEVAGKVFKIVHDKQRGPLTLVRILRGEIKRGMRLISA 358
            |:                           |.|.|.:...|.:||.|:...:.||.:::|..|:|.
  Fly   335 GL---------------------------VEGIVVESKTDPRRGKLSTAIVSRGTLRKGSVLLSG 372

  Fly   359 RGQAEVVSKLY----EPLADEYREVSAVQSGDVVICAGLKSTVTGDLLTSSQSALK-NAQKRYKQ 418
            ...|: |..|:    :||::      |.....|.|....:..:.|||:...::..| :|..:|::
  Fly   373 LAHAK-VRGLFDHNGQPLSE------APPGTPVEILGWRELPLAGDLILEVETEKKAHAVLKYRE 430

  Fly   419 SLGNTAAKVEEDDELDESDELFAIDPQIPDAVYFCSIEPPSVSSQTAME--QALKQLQREDPSLR 481
            ............||:.:.:|..       .|.|....|...::.:..|.  |.:||:...:...|
  Fly   431 HESQQEKIESSSDEIRKKEEEH-------QAKYRAEREARRLAGRFRMRGGQRVKQVDENEGKPR 488

  Fly   482 VSYDSVTGQTVLGGMGELHMDIIKSRILSE--------YKI-DVDLGPLQIA-------YKETIE 530
            ||. .:.|.  :.|..|..:|::::...:|        |.: :|..|.|::|       |...:|
  Fly   489 VSV-IIKGD--VHGSVEAILDVLETYNSNESCRLDIVHYGVGNVTEGDLELAKAFHAIIYAFAVE 550

  Fly   531 APALTTLSVEKEIAGSKQSVSITLEVVKNQAELFSLDKSP----DNLPNLNTLRPRILQVLRK 589
            .|   .|...||:  :.:|.:|...::.:..|..|....|    :.|...|.|:..::...||
  Fly   551 TP---QLKAAKEV--NIRSYNIIYRLIDDLKEQLSSKLPPVEVEEVLGEANVLQNFLINEGRK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRRF2	NP_732771.2	PRK12739	31..733	CDD:237185	124/583 (21%)
mIF2	NP_651621.2	InfB	158..689	CDD:223606	124/583 (21%)
		IF2_eIF5B	163..327	CDD:206674	56/251 (22%)
		IF2_mtIF2_II	336..431	CDD:293903	26/128 (20%)
		IF-2	482..575	CDD:288813	21/100 (21%)
		mtIF2_IVc	593..680	CDD:293893	4/16 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464612
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930