Protein Alignment mRRF2 and Gfm2

DIOPT Version :10

• Sequence 1: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_001094135.1
• Gene: Gfm2 / 294672
• RGDID: 1309854
• Length: 779
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 305/750 - (40%)
• Similarity: 455/750 - (60%)
• Gaps: 54/750 - (7%)

  Fly    27 RSYSS---------------------KIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGN 70
            |||||                     |||||||:|||||||||||||:|:|:|.||:||:|..|:
  Rat    43 RSYSSPPGIVGNEVKSLHSIINPPVAKIRNIGIMAHIDAGKTTTTERILYYSGYTRSLGDVDDGD 107

  Fly    71 TVTDYLTQERERGITICSSAVTFSWNDHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGV 135
            ||||::.|||||||||.|:|||..|..:|:||:|||||:|||:|||:.|..:||.|.|.|.:|||
  Rat   108 TVTDFMAQERERGITIQSAAVTLDWKGYRVNLIDTPGHVDFTLEVERCLRVLDGAVAVFDASAGV 172

  Fly   136 EAQTVTVWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAIND 200
            ||||:|||.||||||:||:.|:||||:..|.|...|..:::||:.:|:.||.|:........:.|
  Rat   173 EAQTLTVWRQADKHKIPRICFLNKMDKTGASFNYAVESIREKLKAKPLILQLPIGEARTFQGVVD 237

  Fly   201 VITLERLSW-QQKDLGRSYRNVKLEPSDDLRLLQ---EKRNELIDQLSGLDDELADVVIS--TES 259
            |:..|:|.| ...|.|:.:....|..:.|..||:   |.||.||:|::.||||.||:|:.  :|.
  Rat   238 VVNREKLIWNSDSDDGKDFERKPLSEASDPTLLKETVEARNSLIEQVADLDDEFADLVLGEFSED 302

  Fly   260 FDNVDNALIERALRRATTQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQ-IYDCFGTEV 323
            ||.|....::.|:.|.|..|..||||.|||.||.|:|.|:|||..|||:||||.. ....:..::
  Rat   303 FDLVPAEKLQAAIHRVTLAQAAVPVLCGSALKNKGVQPLLDAVTTYLPSPEEREHGFLQWYKGDL 367

  Fly   324 AGKVFKIVHDKQRGPLTLVRILRGEIKRGMRLISA-RGQAEVVSKLYEPLADEYREVSAVQSGDV 387
            ....||::||||||||..:||..|.:.....:.:. |...|.:|:|..|.||::.|:.::.:|::
  Rat   368 CALAFKVLHDKQRGPLVFLRIYSGTLTPQSAVHNVNRNCTERMSRLLLPFADQHVEIPSLTAGNI 432

  Fly   388 VICAGLKSTVTGDLLTSSQSALKNAQKRYKQSLGNTAAKVE-EDDELDESDELFAIDPQIPDAVY 451
            .:..|||.|.|||.:.||:|:...|.:|        |.|.| :...:.|::.:.....:||:.|:
  Rat   433 ALTVGLKQTATGDTIVSSKSSALAAARR--------AGKGERKPGRISEAESVLLAGVEIPEPVF 489

  Fly   452 FCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKSRILSEYKIDV 516
            ||:|||||.:.|..::.||:.||||||||:|..|..:|||||.||||||::||..||..||.::.
  Rat   490 FCTIEPPSAAKQPDLDHALEHLQREDPSLKVKLDPDSGQTVLCGMGELHIEIIHDRIKREYGLET 554

  Fly   517 DLGPLQIAYKETIEAPALTTLSVEKEIAGSKQSVSITLEVVKNQAELFSLDKSPDNLPNL---NT 578
            .|||||:||:|||......|.::::.:...:......|||  ..||      .|..:..:   ::
  Rat   555 YLGPLQVAYRETILNSVRATDTLDRVLGDKRHFARAELEV--RPAE------EPCGVATIEYADS 611

  Fly   579 LRPRILQVLRKGSISALE----RGPRVGGQVVETQIRLHNATIGRGTADSFVMATAAQCVQKLLS 639
            :...:||..|:...:|:.    :||.:|..:.:..:.||:..|..||:.:.|.|..::||||.|.
  Rat   612 VGEDLLQAPREDIENAVHSACLQGPLLGSPIQDVAVTLHSLMIHPGTSTTMVTACISRCVQKALK 676

  Fly   640 TSGTRLLEPIMALQIVAPSERISGIMADLSRRRALINDVLPKGERNKMILVNAPLAELSGYSSAL 704
            .:..::|||:|:|::....|.:|.::|||::||..|.::..: :.||::|...||||:.|||:.|
  Rat   677 KADKQVLEPLMSLEVTVSREYLSPVLADLAQRRGNIQEIQTR-QDNKVVLGFVPLAEIMGYSTVL 740

  Fly   705 RTISSGTASMTMQPCGFSSMNSVDESLAERRAQGL 739
            ||::||:|:..::...:.:|:..|:.....:..||
  Rat   741 RTLTSGSATFALELSTYQAMSPQDQRTLLSQRSGL 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRRF2	NP_732771.2	FusA	30..734	CDD:440248	300/740 (41%)
Gfm2	NP_001094135.1	FusA	66..774	CDD:440248	298/724 (41%)