Protein Alignment mRRF2 and Gfm1

DIOPT Version :9

• Sequence 1: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Sequence 2: NP_613057.2
• Gene: Gfm1 / 28030
• MGIID: 107339
• Length: 751
• Species: Mus musculus
• Alignment Length: 764
• Identity: 234/764 - (30%)
• Similarity: 374/764 - (48%)
• Gaps: 90/764 - (11%)

  Fly    18 WHLSNQIWK-RSYSS-------KIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRG----N 70
            |......|| |.:.|       |||||||.||||:||||.|||:|:|.|:...:.|| :|    .
Mouse    24 WQGKQADWKTRRWCSSGPVPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIATMHEV-KGKDGVG 87

  Fly    71 TVTDYLTQERERGITICSSAVTFSWNDHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGV 135
            .|.|.:..||:|||||.|:|....|.|..||::|||||:|||:|||::|..:||.|:||....||
Mouse    88 AVMDSMELERQRGITIQSAATYTMWKDININIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGV 152

  Fly   136 EAQTVTVWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAIND 200
            :.||:||..|..::.:|.|.|:||:||..::..:.:..::.||......:|.|:..|.....|.|
Mouse   153 QCQTMTVSRQMKRYNVPFLTFINKLDRMGSNPSRALQQMRSKLNHNAAFVQIPIGLEGDFKGIID 217

  Fly   201 VITLERLSWQQKDLGRSYRNVKLEPSDDLRLLQEKRNELIDQLSGLDDELADVVISTESFDNVDN 265
            :|. ||..:...|.|:..|..:: |:.......:.|.|||:.::..|::|.::.:. |...:|.:
Mouse   218 LIE-ERAIYFDGDFGQIVRYDEI-PAGLRAAAADHRQELIECVANSDEQLGELFLE-EKIPSVSD 279

  Fly   266 ALIERALRRATTQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQIYDCFGTEVAGKVFKI 330
              ::||:||||..:...||.||||.||.|:|.|:|||..|||.|.| .|.|.......:.:..||
Mouse   280 --LKRAIRRATLSRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSE-VQNYAILNQNDSKEKTKI 341

  Fly   331 VHDKQR------------------GPLTLVRILRGEIKRGMRLISAR-GQAEVVSKLYEPLADEY 376
            :.:.||                  |.||.||..:||:|:|..:.:.| |:...|.:|....||..
Mouse   342 LMNPQRDDSHPFVGLAFKLEAGRFGQLTYVRNYQGELKKGSTIYNTRTGKKVRVQRLVRMHADMM 406

  Fly   377 REVSAVQSGDVVICAGLKSTVTGDLLTSSQSALKNAQKRYKQSLGNTAAKVEEDDELDESDELFA 441
            .:|..|.:||:....|: ...:||..|:.                            |.|| |..
Mouse   407 EDVEEVYAGDICALFGI-DCASGDTFTNK----------------------------DNSD-LSM 441

  Fly   442 IDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDIIKS 506
            ....:|:.|...::.|.:.:......:.:.:..||||:.:|.:|..:.:|::.||||||::|...
Mouse   442 ESIHVPEPVISIAMRPSNKNDLEKFSKGIGRFTREDPTFKVHFDPESKETIVSGMGELHLEIYAQ 506

  Fly   507 RILSEYKIDVDLGPLQIAYKETIEAPALTTLSVEKEIAGSKQ--SVSITLEVV--KNQAEL-FSL 566
            |:..||......|..::|::|||.||.....:.:|:..|:.|  .|...||.:  ::..:| ||.
Mouse   507 RMEREYGCPCITGKPKVAFRETIVAPVPFDFTHKKQSGGAGQFGKVIGVLEPLPPEDYTKLEFSD 571

  Fly   567 DKSPDNLPNLNTLRPRILQVLRKGSISALERGPRVGGQVVETQIRLHNATIGRGTADSFVMATAA 631
            :....|:|.      :.:..:.||.:.|.|:||..|.::...:..|.:.......::......|.
Mouse   572 ETFGSNVPK------QFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAG 630

  Fly   632 QCVQKLLSTSGTR-LLEPIMALQIVAPSERISGIMADLSRRRALI--NDVLPKGERNKMILVNAP 693
            :...|....:||. ::||||:::::||:|....:.|.::||..:|  .|.:   |....:..:.|
Mouse   631 EGALKQALANGTLCIIEPIMSVEVIAPNEFQGTVFAGINRRHGVITGQDGI---EDYFTLYADVP 692

  Fly   694 LAELSGYSSALRTISSGTASMTM-----QPCGFSSMNSVDESLAERRAQ 737
            |..:.|||:.||:.:.|....||     |||..|:...:.....|...|
Mouse   693 LNNMFGYSTELRSCTEGKGEYTMEYCRYQPCSPSTQEELINKYLEATGQ 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mRRF2	NP_732771.2	PRK12739	31..733	CDD:237185	228/744 (31%)
Gfm1	NP_613057.2	EF-G	49..321	CDD:206673	112/277 (40%)
		PRK12740	53..732	CDD:237186	220/724 (30%)
		mtEFG1_II_like	353..432	CDD:293908	22/79 (28%)
		EFG_III	447..522	CDD:293919	21/74 (28%)
		EFG_mtEFG1_IV	525..641	CDD:238715	26/121 (21%)
		mtEFG1_C	647..724	CDD:239764	25/79 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910