| Sequence 1: | NP_732768.1 | Gene: | btn / 42664 | FlyBaseID: | FBgn0014949 | Length: | 158 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_082292.1 | Gene: | Nanog / 71950 | MGIID: | 1919200 | Length: | 305 | Species: | Mus musculus |
| Alignment Length: | 131 | Identity: | 39/131 - (29%) |
|---|---|---|---|
| Similarity: | 61/131 - (46%) | Gaps: | 37/131 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 55 CNEANDQWLQNEAPTGQELP---------SQRSKL--------------RAISSNRKERTAFSKT 96
Fly 97 QLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIKLEE---------QQGS 152
Fly 153 S 153 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| btn | NP_732768.1 | Homeodomain | 87..143 | CDD:459649 | 25/55 (45%) |
| Nanog | NP_082292.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..30 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 46..95 | 9/52 (17%) | |||
| Sufficient for interaction with SALL4. /evidence=ECO:0000269|PubMed:16840789 | 96..155 | 27/58 (47%) | |||
| Homeodomain | 98..153 | CDD:459649 | 25/54 (46%) | ||
| Required for DNA-binding. /evidence=ECO:0000250|UniProtKB:Q9H9S0 | 123..152 | 13/28 (46%) | |||
| PTZ00395 | <190..>250 | CDD:185594 | |||
| 10 X repeats starting with a Trp in each unit | 198..247 | ||||
| Sufficient for transactivation activity | 198..247 | ||||
| Sufficient for strong transactivation activity | 248..305 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||