DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and hoxc8a

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_001005771.1	Gene:	hoxc8a / 449648	ZFINID:	ZDB-GENE-990415-114	Length:	250	Species:	Danio rerio

Alignment Length:	168	Identity:	51/168 - (30%)
Similarity:	73/168 - (43%)	Gaps:	42/168 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YQESYC-------------YEDITKSWLNQTE------GYTDCSYVYDHSASSSYADYNKLETNW 54
            ||::.|             ||.:.:..|..|:      .|.||.   ..::::.......|..|.
Zfish    72 YQQNPCALACHGDATKFYGYEALPRQPLYGTQQEATLAQYPDCK---SSNSTNPGEGQGHLSQNS 133

  Fly    55 CNEANDQWLQNEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEI 119
            .......|::..||                ..|..|..:|:.|..:||.||.::.||||.||.|:
Zfish   134 SPSLMFPWMRPHAP----------------GRRNGRQTYSRYQTLELEKEFLFNPYLTRKRRIEV 182

  Fly   120 AVALELTERQVKVWFQNRRMKCK----RIKLEEQQGSS 153
            :.||.|||||||:||||||||.|    :.|...|:|.:
Zfish   183 SHALSLTERQVKIWFQNRRMKWKKENNKDKFPGQRGEA 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
hoxc8a	NP_001005771.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..152		8/58 (14%)
		Antp-type hexapeptide. /evidence=ECO:0000255	138..143		1/4 (25%)
		Homeobox	153..205	CDD:278475	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..250		3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.900