DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and pnx

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_840087.1	Gene:	pnx / 352939	ZFINID:	ZDB-GENE-030328-42	Length:	182	Species:	Danio rerio

Alignment Length:	154	Identity:	51/154 - (33%)
Similarity:	76/154 - (49%)	Gaps:	27/154 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 YEDITKSWLNQTEGYTDCSYVYDHSASSSYAD-YNKLETNWCNEANDQWLQNEAPTGQELPSQRS 78
            :|:.:.|.|   :|.|          |.|.|| .:..:.|...|..:.....|:|.... |:|..
Zfish     2 HEETSNSTL---QGKT----------SFSIADILDPAKFNGTRETREISNNRESPKTTS-PTQEP 52

  Fly    79 KLRAISS-------NRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQN 136
            ....|::       :::.||||:..||:.||..|..|:||:...|:.||.||.|:|.|||:||||
Zfish    53 SAPNIANASAAKVKSKRIRTAFTLDQLRILERSFQSSHYLSVFERHCIASALGLSETQVKIWFQN 117

  Fly   137 RRMKCKRIKLE----EQQGSSAKT 156
            ||.|.|: :|:    |:|...|.|
Zfish   118 RRTKWKK-ELDGHGGEEQSHCAPT 140

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	29/51 (57%)
pnx	NP_840087.1	Important for interaction with tle3a. /evidence=ECO:0000269\|PubMed:12642490	1..34		11/44 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	24..63		7/39 (18%)
		Homeobox	71..123	CDD:278475	29/51 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810