DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and HOXD3

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_008829.3	Gene:	HOXD3 / 3232	HGNCID:	5137	Length:	432	Species:	Homo sapiens

Alignment Length:	106	Identity:	46/106 - (43%)
Similarity:	62/106 - (58%)	Gaps:	3/106 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SASSSYADYNKLETNWCNEANDQWLQ-NEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLE 102
            :||||.|..:|....|..|:.....| |...|..|  |...|.....::::.|||::..||.:||
Human   148 NASSSSATISKQIFPWMKESRQNSKQKNSCATAGE--SCEDKSPPGPASKRVRTAYTSAQLVELE 210

  Fly   103 AEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKR 143
            .||.::.||.|.||.|:|..|.|||||:|:||||||||.|:
Human   211 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
HOXD3	NP_008829.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	43..62
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..197		14/50 (28%)
		Antp-type hexapeptide	160..165		1/4 (25%)
		Homeobox	198..250	CDD:306543	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	253..280
		DUF4074	369..430	CDD:315871
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..432
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810