Protein Alignment btn and HOXC11

DIOPT Version :10

• Sequence 1: NP_732768.1
• Gene: btn / 42664
• FlyBaseID: FBgn0014949
• Length: 158
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 217
• Identity: 54/217 - (24%)
• Similarity: 85/217 - (39%)
• Gaps: 76/217 - (35%)

  Fly     5 HANVYQESYCYED------------ITKSWLNQTEGYTDCSYVYDHSASSSYAD----YNKLETN 53
            |.|.|...|...|            :|:. |.:.||    ||...|..|:.:|.    |:.:..|
Human    85 HRNSYSSCYAAADELMHRECLPPSTVTEI-LMKNEG----SYGGHHHPSAPHATPAGFYSSVNKN 144

  Fly    54 -WCNEANDQWLQN------------------------EAPTGQEL------------------PS 75
             ...:|.|::..|                        |||....|                  ||
Human   145 SVLPQAFDRFFDNAYCGGGDPPAEPPCSGKGEAKGEPEAPPASGLASRAEAGAEAEAEEENTNPS 209

  Fly    76 QRSKLRAISS------------NRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTER 128
            ......:::.            .||:|..:||.|:::||.||.::.|:.:.:|.:::..|.||:|
Human   210 SSGSAHSVAKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLSRMLNLTDR 274

  Fly   129 QVKVWFQNRRMKCKRIKLEEQQ 150
            |||:||||||||.|::..:..|
Human   275 QVKIWFQNRRMKEKKLSRDRLQ 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeodomain	87..143	CDD:459649	27/55 (49%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		8/70 (11%)
		Homeodomain	233..289	CDD:459649	27/55 (49%)