DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btn and HOXC8

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_073149.1	Gene:	HOXC8 / 3224	HGNCID:	5129	Length:	242	Species:	Homo sapiens

Alignment Length:	154	Identity:	50/154 - (32%)
Similarity:	69/154 - (44%)	Gaps:	38/154 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 YQESYC-------------YEDITKSWL--NQTEG----YTDCSYVYDHSASSSYADYNKLETNW 54
            ||::.|             ||.:.:..|  .|.|.    |.||....:.::|......|:   |.
Human    72 YQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ---NS 133

  Fly    55 CNEANDQWLQNEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEI 119
            .......|::..||                ..|..|..:|:.|..:||.||.::.||||.||.|:
Human   134 SPSLMFPWMRPHAP----------------GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEV 182

  Fly   120 AVALELTERQVKVWFQNRRMKCKR 143
            :.||.|||||||:||||||||.|:
Human   183 SHALGLTERQVKIWFQNRRMKWKK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	114..154		8/58 (14%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeobox	153..205	CDD:306543	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	206..242		0/1 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810