DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and HOXC6

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_004494.1	Gene:	HOXC6 / 3223	HGNCID:	5128	Length:	235	Species:	Homo sapiens

Alignment Length:	132	Identity:	44/132 - (33%)
Similarity:	69/132 - (52%)	Gaps:	27/132 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YDHSASSSYADYNKLETNWCNEANDQWLQNEAPTGQELPSQRSK---------------LRAISS 85
            ||:.::|.|.:.:.|..  |.: |......:....|:..|::.:               ::.::|
Human    70 YDYGSNSFYQEKDMLSN--CRQ-NTLGHNTQTSIAQDFSSEQGRTAPQDQKASIQIYPWMQRMNS 131

  Fly    86 N---------RKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKC 141
            :         |:.|..:|:.|..:||.||.::.||||.||.|||.||.|||||:|:||||||||.
Human   132 HSGVGYGADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKW 196

  Fly   142 KR 143
            |:
Human   197 KK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	32/51 (63%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		0/4 (0%)
		Homeobox	145..198	CDD:395001	32/52 (62%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..235
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810