DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and HOXB1

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_002135.2	Gene:	HOXB1 / 3211	HGNCID:	5111	Length:	301	Species:	Homo sapiens

Alignment Length:	131	Identity:	50/131 - (38%)
Similarity:	66/131 - (50%)	Gaps:	21/131 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SASSSYADY--NKLETNWCNEANDQWLQNEAPTGQEL--------PSQRSKLR--AISSNRKERT 91
            |.:.:|||.  ...||...:|.|       .||.:..        |.:.:|:.  .:.|....||
Human   151 SFAPAYADLLSEDKETPCPSEPN-------TPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRT 208

  Fly    92 AFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIKLEEQQGSSAKT 156
            .|:..||.:||.||.::.||:|.||.|||..|||.|.|||:||||||||.|  |.|.::|.....
Human   209 NFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQK--KREREEGRVPPA 271

  Fly   157 P 157
            |
Human   272 P 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	32/51 (63%)
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..77
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..149
		Antp-type hexapeptide	179..184		0/4 (0%)
		Homeobox	207..259	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..301		9/21 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810