DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and HOXA7

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_008827.2	Gene:	HOXA7 / 3204	HGNCID:	5108	Length:	230	Species:	Homo sapiens

Alignment Length:	160	Identity:	54/160 - (33%)
Similarity:	78/160 - (48%)	Gaps:	27/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NSHANVYQESYCYEDITKSWLNQTEGYTDCSYVYDHSASSSYADYN------KLETNWCNEANDQ 61
            |.::.:||..:            ..||...:..|.:...:|| |.|      .|....|::.::.
Human    56 NVNSPLYQSPF------------ASGYGLGADAYGNLPCASY-DQNIPGLCSDLAKGACDKTDEG 107

  Fly    62 WLQNEAPTGQEL-PSQRSKLRAISSNRKE-RTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALE 124
            .|...|.....: |..||.    ..:||. |..:::.|..:||.||.::.||||.||.|||.||.
Human   108 ALHGAAEANFRIYPWMRSS----GPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALC 168

  Fly   125 LTERQVKVWFQNRRMKCKRIKLEEQQGSSA 154
            |||||:|:||||||||.|  |..:.:|.:|
Human   169 LTERQIKIWFQNRRMKWK--KEHKDEGPTA 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
HOXA7	NP_008827.2	Antp-type hexapeptide	119..124		1/4 (25%)
		Homeobox	134..186	CDD:278475	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..230		3/10 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.810