DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and HOXA3

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_001371264.1	Gene:	HOXA3 / 3200	HGNCID:	5104	Length:	443	Species:	Homo sapiens

Alignment Length:	116	Identity:	42/116 - (36%)
Similarity:	61/116 - (52%)	Gaps:	29/116 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 WCNEANDQWLQ-------------NEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEF 105
            |..|:.....|             :::|.||            :|:::.|||::..||.:||.||
Human   158 WMKESRQNTKQKTSSSSSGESCAGDKSPPGQ------------ASSKRARTAYTSAQLVELEKEF 210

  Fly   106 CYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIKLEEQQGSSAKT 156
            .::.||.|.||.|:|..|.|||||:|:||||||||.|:    :|:|....|
Human   211 HFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK----DQKGKGMLT 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
HOXA3	NP_001371264.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..147
		Antp-type hexapeptide	155..160		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..196		6/48 (13%)
		Homeobox	195..248	CDD:395001	31/52 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	247..338		4/15 (27%)
		DUF4074	378..441	CDD:404218
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810