DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and hoxb8b

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_571256.1	Gene:	hoxb8b / 30420	ZFINID:	ZDB-GENE-980526-291	Length:	247	Species:	Danio rerio

Alignment Length:	182	Identity:	57/182 - (31%)
Similarity:	83/182 - (45%)	Gaps:	39/182 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 HANVYQESYCYEDITKSWLNQTEGYTDCSYVYDHSASSSYADYNKLE------------TNW--C 55
            ||..:.:.|.:.  |.|:.:.:...|.|:..|...|:.:....:.|:            |.:  |
Zfish    51 HAAQFPDFYHHG--TSSFPHASYQQTPCAVAYPGDATGNILGQDGLQKQSFFGAPDSDFTQFGDC 113

  Fly    56 N----EANDQWLQNEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRR 116
            |    ...|.....|..|.|..|..|.:   .:..|:.|..:|:.|..:||.||.::.||||.||
Zfish   114 NLKVSGIRDDLESAEPCTAQLFPWMRPQ---ATGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRR 175

  Fly   117 YEIAVALELTERQVKVWFQNRRMKCKR----------------IKLEEQQGS 152
            .|::.||.|||||||:||||||||.|:                |:.|.|:||
Zfish   176 IEVSHALALTERQVKIWFQNRRMKWKKEHNKDKFPSSKAEQEEIERERQEGS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
hoxb8b	NP_571256.1	Antp-type hexapeptide	134..139		1/4 (25%)
		Homeobox	149..201	CDD:278475	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..247		6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.900