DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and hoxb3a

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_571192.2	Gene:	hoxb3a / 30339	ZFINID:	ZDB-GENE-990415-104	Length:	417	Species:	Danio rerio

Alignment Length:	127	Identity:	47/127 - (37%)
Similarity:	70/127 - (55%)	Gaps:	8/127 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SASSSYADYNKLETN---WCNEANDQWLQ-NEAPTGQELPSQRS----KLRAISSNRKERTAFSK 95
            |.|||.|....|...   |..|:.....| |.:|:.....::.|    .....:::::.|||::.
Zfish   125 SKSSSMATNPTLTKQIFPWMKESRQNTKQKNSSPSASSANAESSGGEKSPPGSAASKRARTAYTS 189

  Fly    96 TQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIKLEEQQGSSAKTP 157
            .||.:||.||.::.||.|.||.|:|..|.|:|||:|:||||||||.|:.:..:..|||:..|
Zfish   190 AQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKSKGIGSSSGGP 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	30/51 (59%)
hoxb3a	NP_571192.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..135		5/9 (56%)
		Antp-type hexapeptide	140..145		1/4 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	147..184		4/36 (11%)
		Homeobox	184..236	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	237..290		4/15 (27%)
		DUF4074	353..415	CDD:290032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	381..417
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810