DRSC/TRiP Functional Genomics Resources

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Protein Alignment btn and Pdx1

DIOPT Version :9

Sequence 1:NP_732768.1 Gene:btn / 42664 FlyBaseID:FBgn0014949 Length:158 Species:Drosophila melanogaster
Sequence 2:NP_074043.4 Gene:Pdx1 / 29535 RGDID:62387 Length:283 Species:Rattus norvegicus


Alignment Length:107 Identity:44/107 - (41%)
Similarity:63/107 - (58%) Gaps:18/107 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 EAPTGQELP---SQRSKLRAISS-------------NRKERTAFSKTQLKQLEAEFCYSNYLTRL 114
            |.|:...||   .:.:|..|..|             |::.|||:::.||.:||.||.::.|::|.
  Rat   110 EEPSRVHLPFPWMKSTKAHAWKSQWAGGAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRP 174

  Fly   115 RRYEIAVALELTERQVKVWFQNRRMKCKRIKLEEQQGSSAKT 156
            ||.|:||.|.||||.:|:||||||||.|  |.|:::.||..|
  Rat   175 RRVELAVMLNLTERHIKIWFQNRRMKWK--KEEDKKRSSGTT 214

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btnNP_732768.1 Homeobox 90..142 CDD:278475 30/51 (59%)
Pdx1NP_074043.4 Transactivation domain 13..73
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..81
Antp-type hexapeptide 118..123 1/4 (25%)
Homeobox 149..203 CDD:395001 31/55 (56%)
Nuclear localization signal. /evidence=ECO:0000250 197..203 5/7 (71%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..283 6/16 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X14
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

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