Protein Alignment btn and NKX2-8

DIOPT Version :10

• Sequence 1: NP_732768.1
• Gene: btn / 42664
• FlyBaseID: FBgn0014949
• Length: 158
• Species: Drosophila melanogaster
• Sequence 2: NP_055175.2
• Gene: NKX2-8 / 26257
• HGNCID: 16364
• Length: 239
• Species: Homo sapiens
• Alignment Length: 143
• Identity: 45/143 - (31%)
• Similarity: 60/143 - (41%)
• Gaps: 31/143 - (21%)

  Fly    17 DITKSWLNQTEGYTDCSYVYDHSASSSYADYNKLETNWCNEANDQWLQNEAPTGQELPSQR--SK 79
            |...:||:...|         |..||   |.:.|||:             .|...:.||.|  |.
Human    38 DPCAAWLDSERG---------HYPSS---DESSLETS-------------PPDSSQRPSARPASP 77

  Fly    80 LRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRI 144
            .......:|.|..|||.|..:||..|....||:...|.::|..|.||..|||:||||.|.|.||.
Human    78 GSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPEREQLASLLRLTPTQVKIWFQNHRYKLKRA 142

  Fly   145 KLEEQQGSSAKTP 157
            :..    .:|::|
Human   143 RAP----GAAESP 151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeodomain	87..143	CDD:459649	25/55 (45%)
NKX2-8	NP_055175.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..87		16/73 (22%)
		Homeodomain	85..141	CDD:459649	25/55 (45%)