DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment btn and Hoxc8

DIOPT Version :9

Sequence 1:NP_732768.1 Gene:btn / 42664 FlyBaseID:FBgn0014949 Length:158 Species:Drosophila melanogaster
Sequence 2:NP_001170797.2 Gene:Hoxc8 / 24460 RGDID:2821 Length:242 Species:Rattus norvegicus


Alignment Length:154 Identity:50/154 - (32%)
Similarity:69/154 - (44%) Gaps:38/154 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 YQESYC-------------YEDITKSWL--NQTEG----YTDCSYVYDHSASSSYADYNKLETNW 54
            ||::.|             ||.:.:..|  .|.|.    |.||....:.::|......|:   |.
  Rat    72 YQQNPCSLSCHGDASKFYGYEALPRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQ---NS 133

  Fly    55 CNEANDQWLQNEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEI 119
            .......|::..||                ..|..|..:|:.|..:||.||.::.||||.||.|:
  Rat   134 SPSLMFPWMRPHAP----------------GRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEV 182

  Fly   120 AVALELTERQVKVWFQNRRMKCKR 143
            :.||.|||||||:||||||||.|:
  Rat   183 SHALGLTERQVKIWFQNRRMKWKK 206

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
btnNP_732768.1 Homeobox 90..142 CDD:278475 31/51 (61%)
Hoxc8NP_001170797.2 Homeobox 153..206 CDD:395001 31/52 (60%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.900

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