DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and Hoxd8

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_032302.2	Gene:	Hoxd8 / 15437	MGIID:	96209	Length:	289	Species:	Mus musculus

Alignment Length:	137	Identity:	49/137 - (35%)
Similarity:	70/137 - (51%)	Gaps:	25/137 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 YCYEDITKS--WLNQTEG----YTDCSYVYDHSASSSYADYNKLETNWCNEANDQWLQNEAPTGQ 71
            |.|:::.:.  :..|.|.    |.||.     |:|.:           ..|..|...|:.:|: |
Mouse   135 YGYDNLQRQPIFTTQQEAELVQYPDCK-----SSSGN-----------IGEDPDHLNQSSSPS-Q 182

  Fly    72 ELPSQRSKLRAISSNRKERTAFSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQN 136
            ..|..|.  :|....|:.|..:|:.|..:||.||.::.||||.||.|::..|.|||||||:||||
Mouse   183 MFPWMRP--QAAPGRRRGRQTYSRFQTLELEKEFLFNPYLTRKRRIEVSHTLALTERQVKIWFQN 245

  Fly   137 RRMKCKR 143
            ||||.|:
Mouse   246 RRMKWKK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	30/51 (59%)
Hoxd8	NP_032302.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	62..125
		COG5576	139..272	CDD:227863	47/133 (35%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	162..184		7/33 (21%)
		Antp-type hexapeptide	183..188		1/4 (25%)
		Homeobox	199..251	CDD:278475	30/51 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	252..289		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900