DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and Hoxd3

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_034598.2	Gene:	Hoxd3 / 15434	MGIID:	96207	Length:	433	Species:	Mus musculus

Alignment Length:	106	Identity:	46/106 - (43%)
Similarity:	61/106 - (57%)	Gaps:	3/106 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 SASSSYADYNKLETNWCNEANDQWLQ-NEAPTGQELPSQRSKLRAISSNRKERTAFSKTQLKQLE 102
            |||||.:..:|....|..|:.....| |...|..|....:|.....|  ::.|||::..||.:||
Mouse   149 SASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPAS--KRVRTAYTSAQLVELE 211

  Fly   103 AEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKR 143
            .||.::.||.|.||.|:|..|.|||||:|:||||||||.|:
Mouse   212 KEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	31/51 (61%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..198		14/50 (28%)
		Antp-type hexapeptide	161..166		1/4 (25%)
		Homeobox	199..251	CDD:278475	31/51 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..280
		DUF4074	370..431	CDD:290032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810