DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment btn and Hoxb2

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_598793.2	Gene:	Hoxb2 / 103889	MGIID:	96183	Length:	354	Species:	Mus musculus

Alignment Length:	106	Identity:	47/106 - (44%)
Similarity:	60/106 - (56%)	Gaps:	26/106 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 WLQNEAPTGQELPSQ--------RSKLRAI----------------SSNRKERTAFSKTQLKQLE 102
            |::.:..|  :.|||        .|.:||.                |.:|:.|||::.|||.:||
Mouse    95 WMKEKKST--KKPSQSAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELE 157

  Fly   103 AEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKR 143
            .||.::.||.|.||.|||..|:||||||||||||||||.||
Mouse   158 KEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKR 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	35/51 (69%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..143		9/49 (18%)
		Antp-type hexapeptide	92..97		1/1 (100%)
		Homeobox	145..197	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		5/6 (83%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810