DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment btn and Hoxa1

DIOPT Version :9

Sequence 1:	NP_732768.1	Gene:	btn / 42664	FlyBaseID:	FBgn0014949	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_037207.2	Gene:	Hoxa1 / 103690132	RGDID:	11414885	Length:	334	Species:	Rattus norvegicus

Alignment Length:	130	Identity:	46/130 - (35%)
Similarity:	68/130 - (52%)	Gaps:	13/130 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 YDHSASSSYADYNKLETNWCNEAND-----QWL---QNEAPTGQELPSQRSKLRAISSNRKERTA 92
            |::|.|..:|.:.:...:..:|.:.     .|:   :|...||:.     .:...:......||.
  Rat   175 YNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKV-----GEYGYVGQPNAVRTN 234

  Fly    93 FSKTQLKQLEAEFCYSNYLTRLRRYEIAVALELTERQVKVWFQNRRMKCKRIKLEEQQGSSAKTP 157
            |:..||.:||.||.::.||||.||.|||.:|:|.|.|||:||||||||.|:.:.|.....|..||
  Rat   235 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 299

Fly 158 157
Rat 300 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
btn	NP_732768.1	Homeobox	90..142	CDD:278475	32/51 (63%)
Hoxa1	NP_037207.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..82
		Interaction with OGT. /evidence=ECO:0000250\|UniProtKB:P09022	74..202		5/26 (19%)
		COG5576	175..>285	CDD:227863	41/114 (36%)
		Antp-type hexapeptide	203..208		1/4 (25%)
		Homeobox	232..284	CDD:278475	32/51 (63%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..334		8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910