DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dph5 and dph5

DIOPT Version :9

Sequence 1:	NP_524452.4	Gene:	Dph5 / 42663	FlyBaseID:	FBgn0024558	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001007387.2	Gene:	dph5 / 492514	ZFINID:	ZDB-GENE-041114-85	Length:	288	Species:	Danio rerio

Alignment Length:	283	Identity:	180/283 - (63%)
Similarity:	217/283 - (76%)	Gaps:	6/283 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFYLIGLGLGDLKDITVKGLEIVKQCSRVYLEMYTSILGCSLEDMQEFYGRPLLLADRDLVEQGA 65
            |.||:||||||.||||||||||:::|||||||.|||||....:.::|:|||.|||||||:|||.|
Zfish     1 MLYLVGLGLGDAKDITVKGLEIIRKCSRVYLEAYTSILTVGKDALEEYYGRELLLADRDMVEQEA 65

  Fly    66 DEILAGAGESDVALLVVGDPFGATTHTDFILRAKEKNIPYKVIHNASIMNAVGCCGLQLYKFGET 130
            ||||.||...|||.||||||||||||:|.:|||....|.|:|||||||||||||||||||.||||
Zfish    66 DEILKGADVCDVAFLVVGDPFGATTHSDLVLRALNAGIQYRVIHNASIMNAVGCCGLQLYNFGET 130

  Fly   131 VSIPYWDETWKPDSFYDKIKLNRLHNMHTLCLLDIKVKEPTPESLMRKRKEYMPPRFMTVAEAAH 195
            |||.:|.:||:|:|||||||.||...:||||||||||||.:.|:|||.||.|.|||:||||:||.
Zfish   131 VSIVFWTDTWRPESFYDKIKKNRDMGLHTLCLLDIKVKEQSMENLMRGRKIYEPPRYMTVAQAAE 195

  Fly   196 QLLSIVEKKDSLEKNTVLNEQSLCVGLARVGQESQQIAVGTLLEMRSTDLGGPLHSLIIPAKEMH 260
            |||.|::.:....:...:.|.::||||||||.|.|.|..|||.|:.|.||.|||||||| :..:|
Zfish   196 QLLEILQNRRDRGEELAMTEDTVCVGLARVGAEDQTIRSGTLRELASCDLEGPLHSLII-SGHLH 259

  Fly   261 PLEVEFLQQYA-----PSIKLDD 278
            ||||:.|:.::     .|:|:.|
Zfish   260 PLEVDMLKLFSSPEGLKSLKMTD 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dph5	NP_524452.4	PTZ00175	1..270	CDD:185500	177/268 (66%)
dph5	NP_001007387.2	PTZ00175	1..270	CDD:185500	177/269 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596780
Domainoid	1	1.000	324	1.000	Domainoid score	I1183
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	354	1.000	Inparanoid score	I2210
OMA	1	1.010	-	-		QHG62266
OrthoDB	1	1.010	-	-		D1018517at2759
OrthoFinder	1	1.000	-	-		FOG0005194
OrthoInspector	1	1.000	-	-		oto40186
orthoMCL	1	0.900	-	-		OOG6_101531
Panther	1	1.100	-	-	LDO	PTHR10882
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3707
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.910