DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN6 and Stambp

DIOPT Version :9

Sequence 1:	NP_524451.1	Gene:	CSN6 / 42661	FlyBaseID:	FBgn0028837	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001349007.1	Gene:	Stambp / 70527	MGIID:	1917777	Length:	424	Species:	Mus musculus

Alignment Length:	169	Identity:	32/169 - (18%)
Similarity:	62/169 - (36%)	Gaps:	54/169 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 DMSAKPSTSSSAAAGSSMAVDKTADQNPQ-----------------PQGNIMAAAGTSGSVTISL 56
            |:|..|.......:....||:...|..|:                 .:|||.
Mouse     6 DVSLPPQDRVRILSQLGSAVELNEDIPPRRYYRSGVEIIRMASVYSEEGNIE------------- 57

  Fly    57 HPLVIMNISEHWTRFRAQHGEPRQVYGALIGKQKG-----RNIEIMNSFELKTDVIGDETVINKD 116
            |..::.|  ::.|.|..:..:.|....|:|.::|.     :::....:.||||:::...|   |:
Mouse    58 HAFILYN--KYITLFIEKLPKHRDYKSAIIPEKKDAVKKLKSVAFPKAEELKTELLRRYT---KE 117

  Fly   117 YYNKKEQQYKQVFSDLDFIGWYTTGDNPTADDIKIQRQI 155
            |...||::.|:              :...|.:|.||:::
Mouse   118 YEQYKERKKKE--------------EEELARNIAIQQEL 142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN6	NP_524451.1	MPN_CSN6	52..335	CDD:163694	22/109 (20%)
Stambp	NP_001349007.1	Interaction with CHMP3. /evidence=ECO:0000250	1..127		27/138 (20%)
		USP8_dimer	8..114	CDD:370218	21/120 (18%)
		Interaction with STAM1. /evidence=ECO:0000250	227..231
		MPN_AMSH_like	254..424	CDD:163697
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	335..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900