DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN6 and Mpnd

DIOPT Version :9

Sequence 1:	NP_524451.1	Gene:	CSN6 / 42661	FlyBaseID:	FBgn0028837	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_080806.4	Gene:	Mpnd / 68047	MGIID:	1915297	Length:	487	Species:	Mus musculus

Alignment Length:	188	Identity:	37/188 - (19%)
Similarity:	71/188 - (37%)	Gaps:	47/188 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEQMEVDV-------DMSAKPSTSSS---AAAGSSMAVDKT-------------ADQNPQPQGNI 42
            :|:.|.||       |...:|....|   .|......:||.             :.:||.....:
Mouse   180 LEEEEEDVLAGVSSEDKGHRPPGKGSLEPEATPPGKRMDKVPVPIRYCMLGSRDSARNPHTLVEV 244

  Fly    43 MAAAGTSG----SVTISLHPLVIMNISEHWTRFRAQHGEPRQVYGALIGKQKGRN--IEIMNSFE 101
            .:.|..:.    :|.:|.:.|.:::...|.||        .:|.|.|.|:....|  :.::.:|.
Mouse   245 TSFAAINKFQPFNVAVSSNVLFLLDFHCHLTR--------SEVVGYLGGRWDINNQMLTVLRAFP 301

  Fly   102 LKTDVIGDETVINKDYYNKKEQQYKQVF-SDLDFIGWYTTGDN----PTADDIKIQRQ 154
            .::.:...:|....:     |:.|:.:| ..|..:|||.:..:    |:..||..|.:
Mouse   302 CRSRLGDTDTAATVE-----EEIYQVLFLRGLSLVGWYHSHPHSPAVPSLQDIDAQME 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN6	NP_524451.1	MPN_CSN6	52..335	CDD:163694	24/110 (22%)
Mpnd	NP_080806.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..217		8/36 (22%)
		MPN_2A_DUB	252..436	CDD:163698	24/116 (21%)
		JAMM motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01182	335..348		1/12 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900