DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN6 and Cops6

DIOPT Version :9

Sequence 1:	NP_524451.1	Gene:	CSN6 / 42661	FlyBaseID:	FBgn0028837	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001100599.1	Gene:	Cops6 / 304343	RGDID:	1309919	Length:	344	Species:	Rattus norvegicus

Alignment Length:	340	Identity:	195/340 - (57%)
Similarity:	258/340 - (75%)	Gaps:	17/340 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MSAKPSTSSSAAA-------GSS-MAVDKTADQNPQPQGNIMAAAGTSGSVTISLHPLVIMNISE 66
            |:|..:.:::|||       ||| |.||.....        :.|:|.:|||:::||||||:|||:
  Rat    14 MAAAAAAAAAAAAAAANGSGGSSGMEVDAAVPS--------VMASGVTGSVSVALHPLVILNISD 70

  Fly    67 HWTRFRAQHGEPRQVYGALIGKQKGRNIEIMNSFELKTDVIGDETVINKDYYNKKEQQYKQVFSD 131
            ||.|.|:|.|.|.||.|||||||:|||||:||||||.:..:..:.:|:|:||..||:|:||||.:
  Rat    71 HWIRMRSQEGRPMQVIGALIGKQEGRNIEVMNSFELLSHTVEKKIIIDKEYYYTKEEQFKQVFKE 135

  Fly   132 LDFIGWYTTGDNPTADDIKIQRQIAAINECPIMLQLNPLSRSVDHLPLKLFESLIDLVDGEATML 196
            |:|:||||||..|...||.:.:|:..|.|.|:.|:|||:::..| ||:.:|||:||:::||||||
  Rat   136 LEFLGWYTTGGPPDPSDIHVHKQVCEIIESPLFLKLNPMTKHTD-LPVSVFESVIDIINGEATML 199

  Fly   197 FVPLTYTLATEEAERIGVDHVARMTSNESGEKSVVAEHLVAQDSAIKMLNTRIKIVLQYIRDVEA 261
            |..||||||||||||||||||||||:..|||.|.|||||:||.||||||::|:|::|:|::..||
  Rat   200 FAELTYTLATEEAERIGVDHVARMTATGSGENSTVAEHLIAQHSAIKMLHSRVKLILEYVKASEA 264

  Fly   262 GKLRANQEILREAYALCHRLPVMQVPAFQEEFYTQCNDVGLISYLGTLTKGCNDMHHFVNKFNML 326
            |::..|.|||||||||||.|||:....|:.:||.|||||||::||||:||.||.|:.||||||:|
  Rat   265 GEVPFNHEILREAYALCHCLPVLSTDKFKTDFYDQCNDVGLMAYLGTITKTCNTMNQFVNKFNVL 329

  Fly   327 YDRQGSARRMRGLYY 341
            |||||..||||||::
  Rat   330 YDRQGIGRRMRGLFF 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN6	NP_524451.1	MPN_CSN6	52..335	CDD:163694	174/282 (62%)
Cops6	NP_001100599.1	MPN_CSN6	56..338	CDD:163694	174/282 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340984
Domainoid	1	1.000	158	1.000	Domainoid score	I4033
eggNOG	1	0.900	-	-		E1_COG1310
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4977
Inparanoid	1	1.050	398	1.000	Inparanoid score	I1887
OMA	1	1.010	-	-		QHG55514
OrthoDB	1	1.010	-	-		D1455324at2759
OrthoFinder	1	1.000	-	-		FOG0005913
OrthoInspector	1	1.000	-	-		oto97942
orthoMCL	1	0.900	-	-		OOG6_103125
Panther	1	1.100	-	-	LDO	PTHR10540
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4896
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770