Protein Alignment sit and ELOVL3

DIOPT Version :10

• Sequence 1: NP_651063.1
• Gene: sit / 42658
• FlyBaseID: FBgn0038986
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_689523.1
• Gene: ELOVL3 / 83401
• HGNCID: 18047
• Length: 270
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 77/295 - (26%)
• Similarity: 128/295 - (43%)
• Gaps: 82/295 - (27%)

  Fly    12 WNFLFTDLADPRTNDWFLIKSPLPLLGILAFYLFFVLSWGPKFMKDRKPFKLERTLLVYNFFQVA 76
            :||..:....|...:::....|:.|:     || .:::.|..:||:||.|.|:..|::::|   .
Human    18 YNFELSKDMRPFFEEYWATSFPIALI-----YL-VLIAVGQNYMKERKGFNLQGPLILWSF---C 73

  Fly    77 LSVWMVYEGVVIW---------------------------QYYSWRCQPVDWSRTPKAYREARVV 114
            |:::.:...|.:|                           :::||
Human    74 LAIFSILGAVRMWGIMGTVLLTGGLKQTVCFINFIDNSTVKFWSW-------------------- 118

  Fly   115 YVYYLAKITELLDTIFFVLRKNDRQVTFLHVYHH-TVMPMISWGTSKYYPGGHGTFIGW---INS 175
             |:.|:|:.||.||.|.:|||  |.:.|:|.||| ||:...|:|.....|.|     ||   :|.
Human   119 -VFLLSKVIELGDTAFIILRK--RPLIFIHWYHHSTVLVYTSFGYKNKVPAG-----GWFVTMNF 175

  Fly   176 FVHIIMYSYYFLSAFGPQMQKYLWWKKYITNLQMIQ-FCCAFI-------HQTQLLYTDCGYPRW 232
            .||.|||:||.|.|...:..|.|  ...||:||::| |..|.:       .|.|..:|...:..|
Human   176 GVHAIMYTYYTLKAANVKPPKML--PMLITSLQILQMFVGAIVSILTYIWRQDQGCHTTMEHLFW 238

  Fly   233 SVCFTLPNAVFFYFLFNDFYQKSYKKKQAAAKEKA 267
            |....:.    ::.||..|:.::|.:.:..||.|:
Human   239 SFILYMT----YFILFAHFFCQTYIRPKVKAKTKS 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sit	NP_651063.1	ELO	28..252	CDD:460083	69/262 (26%)
ELOVL3	NP_689523.1	ELO	29..266	CDD:460083	71/279 (25%)
		Di-lysine motif. /evidence=ECO:0000255|HAMAP-Rule:MF_03203	266..270		2/4 (50%)