Protein Alignment sit and ELOVL4

DIOPT Version :10

• Sequence 1: NP_651063.1
• Gene: sit / 42658
• FlyBaseID: FBgn0038986
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_073563.1
• Gene: ELOVL4 / 6785
• HGNCID: 14415
• Length: 314
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 125/296 - (42%)
• Similarity: 187/296 - (63%)
• Gaps: 11/296 - (3%)

  Fly     3 AVNATQVDYWNFLFTDLADPRTNDWFLIKSPLPLLGILAFYLFFVLSW-GPKFMKDRKPFKLERT 66
            |:|.| |:::.:.:: :||.|..:|.|::||.|.|.|...||.||  | |||:||||:||::...
Human    18 ALNDT-VEFYRWTWS-IADKRVENWPLMQSPWPTLSISTLYLLFV--WLGPKWMKDREPFQMRLV 78

  Fly    67 LLVYNFFQVALSVWMVYEGVVIWQY---YSWRCQPVDWSRTPKAYREARVVYVYYLAKITELLDT 128
            |::|||..|.|::: ::..:.:..|   ||:.||.||:|......|.|..::.|:::|..|.|||
Human    79 LIIYNFGMVLLNLF-IFRELFMGSYNAGYSYICQSVDYSNNVHEVRIAAALWWYFVSKGVEYLDT 142

  Fly   129 IFFVLRKNDRQVTFLHVYHHTVMPMISWGTSKYYPGGHGTFIGWINSFVHIIMYSYYFLSAFGPQ 193
            :||:|||.:.||:|||||||..|..:.|...|:..||...|...:|||:|:||||||.|:||||.
Human   143 VFFILRKKNNQVSFLHVYHHCTMFTLWWIGIKWVAGGQAFFGAQLNSFIHVIMYSYYGLTAFGPW 207

  Fly   194 MQKYLWWKKYITNLQMIQFCCAFIHQTQLLYTDCGYPRWSVCFTLPNAVFFYFLFNDFYQKSYKK 258
            :|||||||:|:|.||:|||.....|....|||||.:|:|.....:..|:.|.|||.:||.::||:
Human   208 IQKYLWWKRYLTMLQLIQFHVTIGHTALSLYTDCPFPKWMHWALIAYAISFIFLFLNFYIRTYKE 272

  Fly   259 -KQAAAKEKALSADNNNDGCAKDLNKAIQLQQEKQK 293
             |:..|.:.|::..:.| |.:|...:.:....:|||
Human   273 PKKPKAGKTAMNGISAN-GVSKSEKQLMIENGKKQK 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sit	NP_651063.1	ELO	28..252	CDD:460083	104/227 (46%)
ELOVL4	NP_073563.1	ELO	41..278	CDD:460083	109/239 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	275..314		8/34 (24%)
		Di-lysine motif. /evidence=ECO:0000255|HAMAP-Rule:MF_03204	310..314