DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sit and Elovl2

DIOPT Version :9

Sequence 1:	NP_651063.1	Gene:	sit / 42658	FlyBaseID:	FBgn0038986	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_062296.1	Gene:	Elovl2 / 54326	MGIID:	1858960	Length:	292	Species:	Mus musculus

Alignment Length:	262	Identity:	105/262 - (40%)
Similarity:	142/262 - (54%)	Gaps:	10/262 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DPRTNDWFLIKSPLPLLGILAFYLFFVLSW-GPKFMKDRKPFKLERTLLVYNFFQVALSVWMVYE 84
            |.|...|||:.|.||...:...||..:  | |.|:||:|....|...|.:||.....||.:|:.|
Mouse    23 DSRVRGWFLLDSYLPTFILTITYLLSI--WLGNKYMKNRPALSLRGILTLYNLAITLLSAYMLVE 85

  Fly    85 GVV-IWQ-YYSWRCQPVDWSRTPKAYREARVVYVYYLAKITELLDTIFFVLRKNDRQVTFLHVYH 147
            .:: .|: .|:.:||.:| |......|.|:|::.||.:|:.|.||||||||||...|:|||||||
Mouse    86 LILSSWEGGYNLQCQNLD-SAGEGDVRVAKVLWWYYFSKLVEFLDTIFFVLRKKTNQITFLHVYH 149

  Fly   148 HTVMPMISWGTSKYYPGGHGTFIGWINSFVHIIMYSYYFLSAFGPQMQKYLWWKKYITNLQMIQF 212
            |..|..|.|....:.|.|...|...:|||:||:|||||.||.| |.|.||||||||:|..|::||
Mouse   150 HASMFNIWWCVLNWIPCGQSFFGPTLNSFIHILMYSYYGLSVF-PSMHKYLWWKKYLTQAQLVQF 213

  Fly   213 CCAFIHQTQLLYTDCGYPRWSVCFTLPNAVFFYFLFNDFYQKSYKKKQAAAKEKALSADNNNDGC 277
            .....|....:...||:|...:.|.....:....||.:||.::|:||..   :|.|......:|.
Mouse   214 VLTITHTLSAVVKPCGFPFGCLIFQSSYMMTLVILFLNFYIQTYRKKPV---KKELQEKEVKNGF 275

  Fly   278 AK 279
            .|
Mouse   276 PK 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sit	NP_651063.1	ELO	28..252	CDD:279492	93/226 (41%)
Elovl2	NP_062296.1	ELO	30..264	CDD:307345	98/240 (41%)
Elovl2	NP_062296.1	Di-lysine motif. /evidence=ECO:0000255\|HAMAP-Rule:MF_03202	289..292
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3071
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1094172at2759
OrthoFinder	1	1.000	-	-		FOG0000078
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X54
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820