Protein Alignment AdipoR and IZH2

DIOPT Version :10

• Sequence 1: NP_651061.1
• Gene: AdipoR / 42656
• FlyBaseID: FBgn0038984
• Length: 444
• Species: Drosophila melanogaster
• Sequence 2: NP_014641.2
• Gene: IZH2 / 854160
• SGDID: S000005362
• Length: 317
• Species: Saccharomyces cerevisiae
• Alignment Length: 292
• Identity: 117/292 - (40%)
• Similarity: 169/292 - (57%)
• Gaps: 19/292 - (6%)

  Fly   139 GALAHNAAE--QAEEFVRKVWEASWKVCHYKNLPKWLQDNDFLHRGHRPPLPSFRACFKSIFRVH 201
            |..:.|.||  :|::.:|:::  ||     ..:|:|.:||||:..|:.....||...|||:|.:|
Yeast    20 GKTSANPAEVAKAKKVLRRLY--SW-----DEIPEWQRDNDFILHGYVKETSSFIETFKSLFYLH 77

  Fly   202 TETGNIWTHLLGCIAFIGVALYFISRPSVEIQTQ--EKIVFGAFFIGAIVCLGFSFAFHTLSCHS 264
            .|:.||::||:..:.|..|.|...|...|...|.  :.:|...|:.||..||..|.:||.|..||
Yeast    78 NESVNIYSHLIPALGFFTVLLLDKSTIKVFATTTWLDHMVIDLFYSGAFACLILSSSFHCLKSHS 142

  Fly   265 VEMGRLFSKLDYCGIALLIMGSFVPWLYYGFYCHYQPKVIYLSVVSILGILSIVVSLWDKFSEPA 329
            :.:..|.:||||.||.:||:.|.|..||||::..:....::..:....||...:|||.|||.:..
Yeast   143 LRIATLGNKLDYLGICILIVTSMVSILYYGYFEKFSLFCLFALITVSFGIACSIVSLKDKFRKRE 207

  Fly   330 LRPLRAGVFMSFGLSGVIPAIH----YSIMEGWFSQMSRASLGWLILMGLLYILGALLYALRVPE 390
            .||.|||:|:.||||.:||...    ||..|.|    ::..|.|::|.|:|||:||:||.:|.||
Yeast   208 WRPYRAGLFVCFGLSSIIPIFSGLYCYSFSEIW----TQIQLFWVLLGGVLYIIGAVLYGMRFPE 268

  Fly   391 RWFPGKFDIWGQSHQIFHILVIAAAFVHYHGI 422
            :..||||||||.|||:||.||:.||..|..|:
Yeast   269 KICPGKFDIWGHSHQLFHFLVVIAALCHLRGL 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdipoR	NP_651061.1	HlyIII	198..419	CDD:427098	95/226 (42%)
IZH2	NP_014641.2	HlyIII	74..297	CDD:427098	95/226 (42%)